ArticleJournal of veterinary internal medicine2017
Repeatability of Oral Sugar Test Results, Glucagon-Like Peptide-1 Measurements, and Serum High-Molecular-Weight Adiponectin Concentrations in Horses.
Article in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Leucine, pyridoxine and resveratrol supplementation alter metabolic parameters in ponies with equine metabolic syndrome.Equine veterinary journal · 2026Article
- Echocardiographic characteristics and evidence of ventricular remodeling in subclinical insulin-dysregulated Warmblood horses.Journal of veterinary internal medicine · 2026Article
- Prevalence of insulin dysregulation in a sport horse population as determined by traditional and stall-side testing.Equine veterinary journal · 2026Article
- High molecular weight adiponectin as an adjunct biomarker for insulin dysregulation in equids.Journal of veterinary internal medicine · 2026Article
- Evaluation of an Immunoturbidometric Assay for Measurement of Total Adiponectin Concentration in Equine Serum Samples.Veterinary clinical pathology · 2026Article
- Evaluation of the tolerance and effects of 1-deoxynojirimycin on insulin and glucose dynamics in healthy horses and horses at risk for insulin dysregulation.Journal of veterinary internal medicine · 2026Article
- Effects of pasture consumption and obesity on insulin dysregulation and adiponectin concentrations in UK native-breed ponies.Equine veterinary journal · 2026Article
- Oligosaccharide feed supplementation reduces plasma insulin in geldings with Equine Metabolic Syndrome.Frontiers in microbiomes · 2023Article
- Variation in insulin response to oral sugar test in a cohort of horses throughout the year and evaluation of risk factors for insulin dysregulation.Equine veterinary journal · 2022Article
- Effect of a GLP-1 mimetic on the insulin response to oral sugar testing in horses.BMC veterinary research · 2022Article
- Diagnostic evaluation of insulin and glucose dynamics in light-breed horses receiving dexamethasone.The Canadian veterinary journal = La revue veterinaire canadienne · 2022Article
- Systemic Administration of Rejuvenated Adipose-Derived Mesenchymal Stem Cells Improves Liver Metabolism in Equine Metabolic Syndrome (EMS)- New Approach in Veterinary Regenerative Medicine.Stem cell reviews and reports · 2019Article
- Enteroinsular axis response to carbohydrates and fasting in healthy newborn foals.Journal of veterinary internal medicine · 2019Article
- Effect of thyrotropin-releasing hormone stimulation testing on the oral sugar test in horses when performed as a combined protocol.Journal of veterinary internal medicine · 2019Article
- Comparison of the glucose and insulin responses of horses to 2 formulations of corn syrup.The Canadian veterinary journal = La revue veterinaire canadienne · 2019Article
- ECEIM consensus statement on equine metabolic syndrome.Journal of veterinary internal medicine · 2019Article
- Retrospective analysis of insulin responses to standard dosed oral glucose tests (OGTs) via naso-gastric tubing towards definition of an objective cut-off value.Acta veterinaria Scandinavica · 2018Article
- Effect of phenylbutazone administration on the enteroinsular axis in horses with insulin dysregulation.Journal of veterinary internal medicineArticle
- Comparison of a customized glycemic pellets challenge with the oral sugar test to measure glycemic and insulinemic responses in horses.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRepeatability of the oral sugar test (OST) has not been evaluated.
objectivesWe hypothesized that OST glucose, insulin, active (aGLP-1) and total (tGLP-1) glucagon-like peptide 1, and high-molecular-weight (HMW) adiponectin results would be repeatable. ANIMALS: Fifty-three horses from a Tennessee research facility (n = 23) and private practice in Missouri (n = 30), including animals with medical histories of equine metabolic syndrome.
methodsTwo OSTs were performed 7-14 days apart and plasma glucose and insulin concentrations were measured at 0, 60, and 75 minutes; a positive result was defined as detection of an insulin concentration >45 μU/mL at 60 or 75 minutes. Plasma aGLP-1 and serum tGLP-1 concentrations at 75 minutes and serum HMW adiponectin concentrations at 0 minute were measured in the Missouri group. Bland-Altman analyses were performed.
resultsNo adverse events were reported. Bland-Altman analysis indicated mean ± SD bias of 1.5 ± 14.8 μU/mL (95% confidence interval [CI], -27.6 to 30.5 μU/mL) and 1.2 ± 16.1 μU/mL (95% CI, -30.4 to 32.8 μU/mL) for insulin concentrations at 60 and 75 minutes, respectively. There was 91 and 83% agreement in test interpretation between test days for OST insulin results for all horses in the Tennessee and Missouri groups, respectively. CONCLUSIONS AND CLINICAL IMPORTANCE: Repeatability of the OST was acceptable when values obtained from Bland-Altman analyses were evaluated, and there was good agreement in binary (negative/positive) test interpretation for insulin concentrations. However, wide 95% CIs were detected for insulin concentrations.
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