Evidence map›Paper›PMID 28543689›Full record

ArticleJournal of neuroscience research2018

Mild cognitive impairment and structural brain abnormalities in a sexagenarian with a history of childhood traumatic brain injury.

John Darrell Van Horn, Andrei Irimia, Carinna M Torgerson, Avnish Bhattrai, Zachary Jacokes, Paul M Vespa

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroscience research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John Darrell Van HornUSC Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California.ORCID 0000-0003-1537-0816
Andrei IrimiaUSC Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California.
Carinna M TorgersonUSC Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California.
Avnish BhattraiUSC Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California.
Zachary JacokesUSC Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, California.
Paul M VespaDepartment of Neurosurgery, University of California Los Angeles, Los Angeles, California.

Funding

TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
Multimodality Image-Based Assessment System for Traumatic Brain InjuryR44NS081792 · NINDS · KITWARE, INC. · PI AYLWARD, STEPHEN R, NIETHAMMER, MARC · 2015 to 2016
$1.3M
NIBIB NIH HHS P41 EB015922NINDS NIH HHS R44 NS081792
6 · The paper itself

Abstract

In this report, we present a case study involving an older, female patient with a history of pediatric traumatic brain injury (TBI). Magnetic resonance imaging and diffusion tensor imaging volumes were acquired from the volunteer in question, her brain volumetrics and morphometrics were extracted, and these were then systematically compared against corresponding metrics obtained from a large sample of older healthy control (HC) subjects as well as from subjects in various stages of mild cognitive impairment (MCI) and Alzheimer disease (AD). Our analyses find the patient's brain morphometry and connectivity most similar to those of patients classified as having early-onset MCI, in contrast to HC, late MCI, and AD samples. Our examination will be of particular interest to those interested in assessing the clinical course in older patients having suffered TBI earlier in life, in contradistinction to those who experience incidents of head injury during aging.

Indexed as

AgedAlzheimer DiseaseBrainBrain Injuries, TraumaticChildCognitive DysfunctionCognitive ReserveDiffusion Tensor ImagingFemaleHealthy VolunteersHumansMagnetic Resonance ImagingPresenilinsRisk FactorsPresenilinsagingmild cognitive impairmenttraumatic brain injury

Identifiers

PMID28543689
PMCPMC5696124

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.