Evidence map›Paper›PMID 28543529›Full record

ArticleThe Journal of physiology2017

Kir2.1 and K2P1 channels reconstitute two levels of resting membrane potential in cardiomyocytes.

Dongchuan Zuo, Kuihao Chen, Min Zhou, Zheng Liu, Haijun Chen

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Maturing heart muscle cells: Mechanisms and transcriptomic insights.Seminars in cell & developmental biology · 2021
    Review
  7. Article
  8. Kir2 inward rectification-controlled precise and dynamic balances between Kir2 and HCN currents initiate pacemaking activity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2018
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Dongchuan ZuoDepartment of Biological Sciences, University at Albany, State University of New York, Albany, NY, USA.ORCID 0000-0002-2243-9124
Kuihao ChenDepartment of Biological Sciences, University at Albany, State University of New York, Albany, NY, USA.
Min ZhouDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Zheng LiuDepartment of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.ORCID 0000-0001-6952-3406
Haijun ChenDepartment of Biological Sciences, University at Albany, State University of New York, Albany, NY, USA.ORCID 0000-0002-8061-1949
Albany State University · USThe Ohio State University Wexner Medical Center · USTongji University · CN

Funding

Dynamic ion selectivity of K2P channels and paradoxical depolarizationR01GM102943 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI CHEN, HAIJUN · 2012 to 2016
$1.4M
NIGMS NIH HHS R01 GM102943
6 · The paper itself

Abstract

key pointsOutward and inward background currents across the cell membrane balance, determining resting membrane potential. Inward rectifier K ABSTRACT: Inward rectifier K

Indexed as

AnimalsCells, CulturedCHO CellsCricetulusHumansMembrane PotentialsMiceMyocytes, CardiacPotassium Channels, Inwardly RectifyingProtein IsoformsPotassium Channels, Inwardly RectifyingProtein IsoformsK2P1 channelsKir2.1 channelsresting membrane potential

Identifiers

PMID28543529
PMCPMC5538241
OpenAlexW2620452990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.