ArticleJournal of child psychology and psychiatry, and allied disciplines2017
Predictors and pathways of language and motor development in four prospective cohorts of young children in Ghana, Malawi, and Burkina Faso.
Article in Journal of child psychology and psychiatry, and allied disciplines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 8 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Community-Based Child Food Interventions/Supplements for the Prevention of Wasting in Children Up to 5 Years at Risk of Wasting and Nutritional Oedema: A Systematic Review and Meta-Analysis.Nutrition reviews · 2025Pooled it
- Linear growth beyond 24 months and child neurodevelopment in low- and middle-income countries: a systematic review and meta-analysis.BMC pediatrics · 2024Pooled it
- The association of breastfeeding with cognitive development and educational achievement in sub-Saharan Africa: A systematic review.Journal of global health · 2022Pooled it
- Small-quantity lipid-based nutrient supplements for children age 6-24 months: a systematic review and individual participant data meta-analysis of effects on developmental outcomes and effect modifiers.The American journal of clinical nutrition · 2021Pooled it
- Breast Milk Micronutrients and Infant Neurodevelopmental Outcomes: A Systematic Review.Nutrients · 2021Pooled it
- Early Child Development Assessments and Their Associations with Long-Term Academic and Economic Outcomes: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- A systematic literature review of the relation between iron status/anemia in pregnancy and offspring neurodevelopment.European journal of clinical nutrition · 2019Pooled it
- Lipid-based nutrient supplements for maternal, birth, and infant developmental outcomes.The Cochrane database of systematic reviews · 2018Pooled it
- Trial
- Anthropometric and sociodemographic variables, but not preconception or prenatal maternal nutrition supplementation, predict neurodevelopment in offspring of the 'Women First' trial.Maternal & child nutrition · 2024Trial
- Understanding modifiable caregiver factors contributing to child development among young children in rural Malawi.Maternal & child nutrition · 2024Trial
- The relationships between optimal infant feeding practices and child development and attained height at age 2 years and 6-7 years.Maternal & child nutrition · 2024Trial
- A complementary feeding and play intervention improves the home environment and mental development among toddlers in rural India.Maternal & child nutrition · 2020Trial
- A Multisectoral Food-Assisted Maternal and Child Health and Nutrition Program Targeted to Women and Children in the First 1000 Days Increases Attainment of Language and Motor Milestones among Young Burundian Children.The Journal of nutrition · 2019Trial
- Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial.The American journal of clinical nutrition · 2019Trial
- Assessing motor development with wearables in low-resource settings: feasibility in rural Malawi.Pediatric research · 2026Article
- Child Hemoglobin Trajectories across the First 10 Years of Life and Association with Child Cognition and Academic Achievement at 10-11 Years.The Journal of nutrition · 2026Article
- The influence of maternal anemia on neonatal neurodevelopment: a systematic review and meta-analysis.Asian biomedicine : research, reviews and news · 2026Article
- A review of early childhood psychosocial interventions following extreme weather events in low- and middle-income countries.Perspectives in public health · 2025Review
- The effect of early childhood stature on later cognitive functions in Indonesian adolescents: comparation using the National growth reference and the WHO growth standard.BMC pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious reviews have identified 44 risk factors for poor early child development (ECD) in low- and middle-income countries. Further understanding of their relative influence and pathways is needed to inform the design of interventions targeting ECD.
methodsWe conducted path analyses of factors associated with 18-month language and motor development in four prospective cohorts of children who participated in trials conducted as part of the International Lipid-Based Nutrient Supplements (iLiNS) Project in Ghana (n = 1,023), Malawi (n = 675 and 1,385), and Burkina Faso (n = 1,122). In two cohorts, women were enrolled during pregnancy. In two cohorts, infants were enrolled at 6 or 9 months. In multiple linear regression and structural equation models (SEM), we examined 22 out of 44 factors identified in previous reviews, plus 12 additional factors expected to be associated with ECD.
resultsOut of 42 indicators of the 34 factors examined, 6 were associated with 18-month language and/or motor development in 3 or 4 cohorts: child linear and ponderal growth, variety of play materials, activities with caregivers, dietary diversity, and child hemoglobin/iron status. Factors that were not associated with child development were indicators of maternal Hb/iron status, maternal illness and inflammation during pregnancy, maternal perceived stress and depression, exclusive breastfeeding during 6 months postpartum, and child diarrhea, fever, malaria, and acute respiratory infections. Associations between socioeconomic status and language development were consistently mediated to a greater extent by caregiving practices than by maternal or child biomedical conditions, while this pattern for motor development was not consistent across cohorts.
conclusionsKey elements of interventions to ensure quality ECD are likely to be promotion of caregiver activities with children, a variety of play materials, and a diverse diet, and prevention of faltering in linear and ponderal growth and improvement in child hemoglobin/iron status.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.