ArticleJournal of surgical oncology2017
The prognostic importance of scalp location in primary head and neck melanoma.
Article in Journal of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 41 citations in OpenAlex.
- Prognostic Implications of Primary Site in Cutaneous Head and Neck Melanoma After the Implementation of Sentinel Node Biopsy: A SEER-Based Analysis (2011-2020).Annals of surgical oncology · 2026Article
- Scalp Melanoma in a Young Patient With Systemic Sarcoidosis: Multidisciplinary Approach.Clinical case reports · 2026Article
- Dermoscopy of Lentiginous Melanomas and Equivocal Benign Pigmented Macules of the Scalp: A Case-Control Multicentric Study.Dermatology (Basel, Switzerland) · 2024Article
- Scalp Melanoma: A High-Risk Subset of Cutaneous Head and Neck Melanomas with Distinctive Clinicopathological Features.Journal of clinical medicine · 2023Article
- Predictors of Nodal Metastasis in Cutaneous Head and Neck Cancers.Current oncology reports · 2022Review
- Do Oncologic Outcomes From Head and Neck Versus Truncal and Extremity Melanoma Differ? A Single-Institution Single-Subspecialty Experience.The American surgeon · 2022Article
- Primary Alopecia Neoplastica: A Novel Case Report and Literature Review.Skin appendage disorders · 2021Article
- Head & neck melanoma: A 22-year experience of recurrence following sentinel lymph node biopsy.Laryngoscope investigative otolaryngology · 2021Article
- Flat scalp melanoma dermoscopic and reflectance confocal microscopy features correspond to histopathologic type and lesion location.Journal of the European Academy of Dermatology and Venereology : JEADV · 2021Article
- Diagnosis and Management of Melanoma of the Scalp: A Review of the Literature.Clinical, cosmetic and investigational dermatology · 2021Review
- Head and neck cutaneous melanoma: 5-year survival analysis in a Serbian university center.World journal of surgical oncology · 2020Article
- Association of Known Melanoma Risk Factors with Primary Melanoma of the Scalp and Neck.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020Article
- CT and MRI features of scalp lesions.La Radiologia medica · 2019Review
- Prognostic Value of Multiple Draining Lymph Node Basins in Melanoma: A Matched-Pair Analysis Based on the John Wayne Cancer Institute Experience.Frontiers in oncology · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesFor patients with cutaneous melanoma, primary tumors located in the head and neck is associated with poor outcomes. The reason for this difference and whether it is applicable to all locations within the head and neck remains unclear. We hypothesized that scalp melanoma is uniquely distinguished from other anatomic sites and is independently responsible for the poor prognosis of head and neck melanoma.
methodsQuery and analysis of a prospectively maintained melanoma database of all patients treated for primary cutaneous melanoma from 1971 to 2010.
resultsOf 11 384 patients identified, 7% (n = 799) of lesions originated on the scalp. Scalp primaries were more often found in males and were associated with increased Breslow thickness and were more frequently ulcerated compared to all other anatomic sites (P = 0.0001). On multivariate analysis, scalp location was an independent predictor of worse melanoma-specific (HR 1.75; CI 1.50-2.04; P < 0.0001) and overall survival (HR 1.62; CI 1.41-1.86; P < 0.0001).
conclusionsThis, the largest series examining scalp melanoma, confirms that scalp location is independently responsible for the negative prognosis associated with head and neck melanoma. Although the pathophysiology of this difference remains to be determined, these data argue for more rigorous surveillance of this anatomic location.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.