Evidence map›Paper›PMID 28543059›Full record

ReviewJournal of medical primatology2017

Natural pathology of the captive chimpanzee (Pan troglodytes): A 35-year review.

Shyamesh Kumar, Hannah Laurence, Michael A Owston, R Mark Sharp, Priscilla Williams, Robert E Lanford, Gene B Hubbard, Edward J Dick

Abstract readReview
In one paragraph

Review in Journal of medical primatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. A 25-Year Retrospective Review of Mortality in Chimpanzees (Animals : an open access journal from MDPI · 2022
    Article
  10. Pathogens (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shyamesh KumarSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.ORCID 0000-0001-9261-2263
Hannah LaurenceSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Michael A OwstonSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
R Mark SharpSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Priscilla WilliamsSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Robert E LanfordSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Gene B HubbardSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Edward J DickSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Texas Biomedical Research Institute · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
WNV REPLIVAX VACCINE IN NON-HUMAN PRIMATESP51RR013986 · NCRR · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI GAUDUIN, MARIE-CLAIRE ELISABETH · 1999 to 2011
$79.1M
NIH-Owned Chimpanzee Research Resource at the SNPRCU42OD011184 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI LANFORD, ROBERT E · 2012 to 2015
$4.0M
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR016228 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 2001 to 2001
$1.9M
NCRR NIH HHS C06 RR016228NCRR NIH HHS P51 RR013986NIH HHS P51 OD011133NIH HHS U42 OD011184
6 · The paper itself

Abstract

We present the spontaneous pathological lesions identified as a result of necropsy or biopsy for 245 chimpanzees (Pan troglodytes) over a 35-year period. A review of the pathology database was performed for all diagnoses on chimpanzees from 1980 to 2014. All morphologic diagnoses, associated system, organ, etiology, and demographic information were reviewed and analyzed. Cardiomyopathy was the most frequent lesion observed followed by hemosiderosis, hyperplasia, nematodiasis, edema, and hemorrhage. The most frequently affected systems were the gastrointestinal, cardiovascular, urogenital, respiratory, and lymphatic/hematopoietic systems. The most common etiology was undetermined, followed by degenerative, physiologic, neoplastic, parasitic, and bacterial. Perinatal and infant animals were mostly affected by physiologic etiologies and chimpanzee-induced trauma. Bacterial and physiologic etiologies were more common in juvenile animals. Degenerative and physiologic (and neoplastic in geriatric animals) etiologies predominated in adult, middle aged, and geriatric chimpanzees.

Indexed as

Pan troglodytesAnimalsApe DiseasesBiopsyIncidenceagingcardiomyopathychimpanzeegeriatriclesionspathologyprimates

Identifiers

PMID28543059
PMCPMC5597465
OpenAlexW2617968725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.