Observational studyJournal of surgical oncology2017
Patient compliance for postoperative radiotherapy and survival outcome of women with stage I endometrioid endometrial cancer.
Observational study in Journal of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Managing unplanned radiotherapy interruptions in Italy: results from an AIRO survey.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Article
- Risk Factors and Survival Impact Associated With Documentation of Radiation Therapy Refusal in Patients With Gynecologic Cancer.International journal of radiation oncology, biology, physics · 2024Article
- Characteristics and survival of patients with gynecological cancers who refuse radiotherapy: a retrospective cohort study.BMC women's health · 2023Article
- Defining Radiation Treatment Interruption Rates During the COVID-19 Pandemic: Findings From an Academic Center in an Underserved Urban Setting.International journal of radiation oncology, biology, physics · 2023Article
- Age-related Differences in Tumour Characteristics and Prognostic Factors for Disease Progression in Cutaneous Squamous Cell Carcinoma of the Head and Neck.Acta dermato-venereologica · 2022Article
- Incidence of and risk factors associated with lung metastases in newly diagnosed epithelial ovarian cancer with a look on prognosis after diagnosis: a population-based cohort study of the SEER database.Archives of gynecology and obstetrics · 2021Article
- Black and Hispanic women are less likely than white women to receive guideline-concordant endometrial cancer treatment.American journal of obstetrics and gynecology · 2020Article
- Guideline-concordant endometrial cancer treatment and survival in the Women's Health Initiative Life and Longevity After Cancer study.International journal of cancer · 2020Article
- Location as Destiny: Identifying Geospatial Disparities in Radiation Treatment Interruption by Neighborhood, Race, and Insurance.International journal of radiation oncology, biology, physics · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
BACKGROUND AND
objectivesTo examine characteristics and survival outcome of women with endometrial cancer who declined postoperative radiotherapy.
methodsA retrospective study was conducted to examine surgically-treated grade 1-2 stage IB and grade 3 stage IA-IB endometrioid endometrial cancer in the Surveillance, Epidemiology, and End Results Program between 1983 and 2013 (n = 10 613). Associations of patient declination for guideline-based postoperative radiotherapy and clinico-pathological demographics or survival outcome were examined on multivariable analysis.
resultsThere were 323 (3.0%) women who declined adjuvant radiotherapy. Women who declined postoperative radiotherapy were more likely to be older, White, Western U.S. residents, and register in recent years (all, adjusted-P < 0.05). On multivariable analysis, patient declination for guideline-based postoperative radiotherapy remained an independent prognostic factor for decreased endometrial cancer-specific survival in unstaged grade 1-2 stage IB or staged/unstated grade 3 stage IA-IB diseases (adjusted-hazard ratio 1.84, 95% confidence interval 1.34-2.51, P = 0.001). Association of patient declination for guideline-based postoperative radiotherapy and decreased overall survival remained independent in the entire cohort on multivariable analysis (adjuvant-hazard ratio 1.71, 95% confidence interval 1.44-2.02, P < 0.001).
conclusionsOur study suggested that patient compliance to guideline-based postoperative radiotherapy is a prognostic factor for women with stage I endometrioid endometrial cancer.
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