ReviewThe Laryngoscope2018
Central voice production and pathophysiology of spasmodic dysphonia.
Review in The Laryngoscope, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03042962 (Brain Networks in Dystonia), which is not on this map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Brain Networks in Dystonia
Who cites it
16 citing papers in PubMed, 57 citations in OpenAlex.
- Assessing the effects of botulinum toxin therapy for spasmodic dysphonia: An Austria-Germany registry.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Enhanced pitch centering in individuals with laryngeal dystonia.Frontiers in human neuroscience · 2026Article
- Spasmodic Dysphonia.World journal of otorhinolaryngology - head and neck surgery · 2025Review
- Minimal Detectable Change of Experienced and Novice Listeners' Ratings of Overall Severity of Voice Quality in Adductor Laryngeal Dystonia.Journal of speech, language, and hearing research : JSLHR · 2025Article
- Patient-Perceived Vocal Effort Immediately Following Voice Tasks in Adductor Laryngeal Dystonia (ADLD).Journal of voice : official journal of the Voice Foundation · 2024Article
- Central Autonomic Mechanisms Involved in the Control of Laryngeal Activity and Vocalization.Biology · 2024Review
- The Effect of Rating Method on Reliability of Judgments of Strain Across Populations.American journal of speech-language pathology · 2024Article
- An Experimental Analysis on Multicepstral Projection Representation Strategies for Dysphonia Detection.Sensors (Basel, Switzerland) · 2023Article
- Effects of Cortical Stimulation on Feedback-Dependent Vocal Control in Non-Human Primates.The Laryngoscope · 2023Article
- Nutritional Biomarkers as Predictors of Dysphonia Severity in Patients with Ischemic Stroke.Nutrients · 2023Article
- Dopamine, vocalization, and astrocytes.Brain and language · 2021Article
- [Application status and prospect of botulinum toxin A in otorhinolaryngological treatment].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020Review
- Laryngeal vibration as a non-invasive neuromodulation therapy for spasmodic dysphonia.Scientific reports · 2019Article
- Atypical somatosensory-motor cortical response during vowel vocalization in spasmodic dysphonia.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2019Article
- Intermittent theta burst stimulation over right somatosensory larynx cortex enhances vocal pitch-regulation in nonsingers.Human brain mapping · 2019Article
- Phenomenology, genetics, and CNS network abnormalities in laryngeal dystonia: A 30-year experience.The Laryngoscope · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveOur ability to speak is complex, and the role of the central nervous system in controlling speech production is often overlooked in the field of otolaryngology. In this brief review, we present an integrated overview of speech production with a focus on the role of central nervous system. The role of central control of voice production is then further discussed in relation to the potential pathophysiology of spasmodic dysphonia (SD). DATA SOURCES: Peer-review articles on central laryngeal control and SD were identified from PUBMED search. Selected articles were augmented with designated relevant publications. REVIEW
methodsPublications that discussed central and peripheral nervous system control of voice production and the central pathophysiology of laryngeal dystonia were chosen.
resultsOur ability to speak is regulated by specialized complex mechanisms coordinated by high-level cortical signaling, brainstem reflexes, peripheral nerves, muscles, and mucosal actions. Recent studies suggest that SD results from a primary central disturbance associated with dysfunction at our highest levels of central voice control. The efficacy of botulinum toxin in treating SD may not be limited solely to its local effect on laryngeal muscles and also may modulate the disorder at the level of the central nervous system.
conclusionFuture therapeutic options that target the central nervous system may help modulate the underlying disorder in SD and allow clinicians to better understand the principal pathophysiology. LEVEL OF EVIDENCE: NA.Laryngoscope, 128:177-183, 2018.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.