Evidence map›Paper›PMID 28542701›Full record

ArticleClinical and experimental immunology2017

Two separate effects contribute to regulatory T cell defect in systemic lupus erythematosus patients and their unaffected relatives.

N Costa, O Marques, S I Godinho, C Carvalho, B Leal, A M Figueiredo, C Vasconcelos, A Marinho, M F Moraes-Fontes, A Gomes da Costa and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

N CostaInstituto Gulbenkian de Ciência, Oeiras, Portugal.
O MarquesUMIB, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Portugal.
S I GodinhoInstituto Gulbenkian de Ciência, Oeiras, Portugal.
C CarvalhoUMIB, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Portugal.
B LealUMIB, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Portugal.
A M FigueiredoUMIB, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Portugal.
C VasconcelosHospital de Santo António, Centro Hospitalar do Porto, Unidade Imunologia Clínica, Porto, Portugal.
A MarinhoHospital de Santo António, Centro Hospitalar do Porto, Unidade Imunologia Clínica, Porto, Portugal.
M F Moraes-FontesInstituto Gulbenkian de Ciência, Oeiras, Portugal.
A Gomes da CostaHospital de Santa Maria, Lisbon, Portugal.
C PonteHospital de Santa Maria, Lisbon, Portugal.
R Campanilho-MarquesHospital de Santa Maria, Lisbon, Portugal.
T CóiasHospital de Santa Maria, Lisbon, Portugal.
A R MartinsCentro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
J F VianaCentro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
M LimaHospital de Santo António, Centro Hospitalar do Porto, Unidade Imunologia Clínica, Porto, Portugal.
B MartinsUMIB, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Portugal.
C FeselInstituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID 0000-0003-3537-5243
Universidade do Porto · PTHospital de Santa Maria · PTHospital de Santo António · PTInstituto Gulbenkian de Ciência · PTCentro Hospitalar de Lisboa Ocidental · PTInstituto Português de Malacologia · PTUnidade Local de Saúde de São José · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Forkhead box P3 (FoxP3)

Indexed as

FamilyAdultAgedFemaleFlow CytometryHumansInterleukin-2Interleukin-2 Receptor alpha SubunitLeukocyte Common AntigensLupus Erythematosus, SystemicLymphocyte ActivationMaleMiddle AgedPhenotypeT-Lymphocytes, RegulatoryUp-RegulationInterleukin-2Interleukin-2 Receptor alpha SubunitLeukocyte Common Antigenscytokinesregulatory T cellssystemic lupus erythematosus

Identifiers

PMID28542701
PMCPMC5543470
OpenAlexW2803366643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.