Evidence map›Paper›PMID 28542601›Full record

ArticlePloS one2017

The epidemiology of Staphylococcus aureus carriage in patients attending inner city sexually transmitted infections and community clinics in Calgary, Canada.

Alejandra Ugarte Torres, Angel Chu, Ron Read, Judy MacDonald, Daniel Gregson, Thomas Louie, Johanna Delongchamp, Linda Ward, Joann McClure, Kunyan Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. The Role of Prophage ϕSa3 in the Adaption ofAntibiotics (Basel, Switzerland) · 2024
    Article
  2. Review
  3. Frontiers in microbiology · 2019
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Alejandra Ugarte TorresDivision of Infectious Diseases, Department of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada.ORCID http://orcid.org/0000-0002-8872-5158
Angel ChuDivision of Infectious Diseases, Department of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada.
Ron ReadDivision of Infectious Diseases, Department of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada.
Judy MacDonaldDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Daniel GregsonDivision of Infectious Diseases, Department of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada.
Thomas LouieDivision of Infectious Diseases, Department of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada.
Johanna DelongchampCentre for Antimicrobial Resistance, Alberta Health Services and University of Calgary, Alberta, Canada.
Linda WardInfection Prevention & Control, Alberta Health Services, Calgary, Alberta, Canada.
Joann McClureCentre for Antimicrobial Resistance, Alberta Health Services and University of Calgary, Alberta, Canada.
Kunyan ZhangDivision of Infectious Diseases, Department of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada.
John ConlyDivision of Infectious Diseases, Department of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada.
Alberta Health Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the nares represent the most common carriage site for traditional hospital-associated strains of Staphylococcus aureus (SA), the predominant site of carriage of SA in the community is less certain.

methodsWe conducted a cross-sectional study in 285 patients attending sexually transmitted diseases and inner-city clinics to evaluate the prevalence, body site colonisation and risk factors associated with carriage of methicillin susceptible SA (MSSA). All isolates were characterized by pulsed field gel electrophoresis, staphylococcal cassette chromosome mec, staphylococcal protein A and multilocus sequence typing.

resultsThe prevalence of colonisation with SA was 57.5% (164/285); 162 (56.8%) participants were colonized with MSSA, and 4 (1.4%) with methicillin-resistant SA (MRSA), 2 of them were co-colonised with both MRSA and MSSA. The most common sites of colonisation were the throat (73.1%), nares (65.2%) and interdigital web spaces of the hand (21.3%). Three out of 4 MRSA isolates were USA300-MRSA strains. Twelve MSSA isolates were closely related to the USA300 CA-MRSA. We identified sexual behaviours such as having more than 6 heterosexual sexual partners in the last 6 months and trimming pubic hair to be independently associated with MSSA colonisation, and more specifically practicing oral sex as a risk factor for throat colonisation.

conclusionThere is a high prevalence of MSSA carriage in this population, with a low prevalence of MRSA. The throat was the most common site of carriage and sexual behaviours were found to be risk factors for MSSA colonisation. Close strain relatedness of MSSA and USA300-MRSA isolates suggests either gain or loss of the SCCmec element, respectively.

Indexed as

AdolescentAdultAgedCanadaCommunity-Acquired InfectionsCross-Sectional StudiesFemaleHumansMaleMethicillin ResistanceMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMiddle AgedMolecular EpidemiologyMolecular TypingSexually Transmitted DiseasesVirulence Factors

Identifiers

PMID28542601
PMCPMC5444836
OpenAlexW2620125259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.