ArticlePloS one2017
Functional restoration of the esophagus after peroral endoscopic myotomy for achalasia.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Paratracheal Air Stripe Sign: A Useful Chest X-Ray Finding for Diagnosis in Patients with Esophageal Achalasia.Digestion · 2026Article
- Association between preoperative pan-esophageal pressurization and peristalsis recovery after per-oral endoscopic myotomy in achalasia.Gastroenterology report · 2026Article
- Loss of Inspiratory Augmentation as a Predictive Factor for the Development of Gastroesophageal Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia.Journal of neurogastroenterology and motility · 2026Article
- Changes in Esophageal Transit Scintigraphy After Peroral Endoscopic Myotomy in Patients With Achalasia.Journal of neurogastroenterology and motility · 2026Article
- Changes in peristalsis following per oral endoscopic myotomy in common esophageal motility disorders.Surgical endoscopy · 2025Article
- Rapid Progression of Nonspecific Esophageal Motor Disorder to Type II Achalasia and Recovery of Peristalsis After Pneumatic Dilation.Journal of neurogastroenterology and motility · 2025Article
- Presence of esophageal contractility after achalasia treatment is associated with improved esophageal emptying.Neurogastroenterology and motility · 2024Article
- Esophageal Motility Patterns After Peroral Endoscopic Myotomy in Patients With Achalasia.Journal of neurogastroenterology and motility · 2021Article
- Morphologic Restoration After Peroral Endoscopic Myotomy in Sigmoid-type Achalasia.Journal of neurogastroenterology and motility · 2020Article
- 2007-2019: a "Third"-Space Odyssey in the Endoscopic Management of Gastrointestinal Tract Diseases.Current treatment options in gastroenterology · 2019Review
- Mechanical dilation, botulinum toxin A injection, and surgical myotomy with fundoplication for treatment of lower esophageal sphincter achalasia-like syndrome in dogs.Journal of veterinary internal medicine · 2019Article
- Correction: Functional restoration of the esophagus after peroral endoscopic myotomy for achalasia.PloS oneArticle
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePeroral endoscopic myotomy (POEM) is a new efficacious treatment option for achalasia. We propose to define "esophageal remodeling" as the functional restoration of the esophagus that involves decreased lower esophageal sphincter (LES) pressure, recovery of esophageal body peristalsis, and reduction of luminal diameter. The aim of this study was to investigate "esophageal remodeling" after POEM for achalasia. MATERIALS AND
methodsWe analyzed data from a prospectively collected database of POEM subjects, which included preoperative and 2-month postoperative Eckardt symptom scores, and results from esophageal high resolution manometry (HRM) and barium esophagogram (BE). We recruited 23 patients (13 male; mean age: 53.9 years) whose preoperative and postoperative HRM and BE results were available, from among 30 patients with achalasia who underwent POEM at two institutions between July 2013 and December 2015.
resultsAll patients achieved clinical treatment success (Eckardt score≤3). Partial recovery of esophageal body peristalsis was noted in 1/5 patients with type I (20%), 6/11 with type II (54.5%), and 7/7 with type III (100%) achalasia after POEM. Pan-esophageal pressurization disappeared after POEM in 10/11 type II achalasia patients. The average diameter of the esophageal body after POEM was significantly decreased in all types of achalasia.
conclusionPOEM provided excellent clinical symptomatic relief and esophageal remodeling in terms of restoration of peristalsis and reduction in diameter of the esophageal body, especially in patients with type III achalasia.
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