ArticlePloS one2017
Factors associated with poor outcomes of continuous renal replacement therapy.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Factors Associated with In-Hospital Mortality after Continuous Renal Replacement Therapy for Critically Ill Patients: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Prognostic associations of urine output in AKI and dialysis vintage in ESKD at continuous kidney replacement therapy initiation in ICU patients.Journal of intensive care · 2026Article
- Intradialytic hypotension and worse outcomes in patients with acute kidney injury requiring intermittent hemodialysis.Kidney research and clinical practice · 2026Article
- Risk factors for adverse short-term and long-term outcomes in children with severe acute kidney injury requiring continuous kidney replacement therapy.Pediatric nephrology (Berlin, Germany) · 2025Article
- Article
- Ensemble Machine Learning for Predicting 90-Day Outcomes and Analyzing Risk Factors in Acute Kidney Injury Requiring Dialysis.Journal of multidisciplinary healthcare · 2024Article
- Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury.BMC nephrology · 2023Article
- Nomogram for Risk Prediction of Mortality for Patients with Critical Cardiovascular Disease Treated by Continuous Renal Replacement Therapy in Coronary Care Unit.Reviews in cardiovascular medicine · 2022Article
- Overview of Renal Replacement Therapy Use in a General Intensive Care Unit.International journal of environmental research and public health · 2022Observational
- Predictors of Mortality in Adults with Acute Kidney Injury Requiring Dialysis: A Cohort Analysis.International journal of nephrology · 2022Article
- The landscape of renal replacement therapy in Veterans Affairs Medical Center intensive care units.Renal failure · 2021Article
- Mortality predictors in critically ill patients with acute kidney injury requiring continuous renal replacement therapy.Kidney research and clinical practice · 2021Article
- Machine learning model to predict hypotension after starting continuous renal replacement therapy.Scientific reports · 2021Article
- Prognostic factors for the short-term mortality of patients with rheumatoid arthritis admitted to intensive care units.BMC rheumatology · 2020Article
- Contemporary Management of Severe Acute Kidney Injury and Refractory Cardiorenal Syndrome: JACC Council Perspectives.Journal of the American College of Cardiology · 2020Review
- Incidence of chronic kidney disease hospitalisations and mortality in Espírito Santo between 1996 to 2017.PloS one · 2019Article
- Palliative care for acute kidney injury patients in the intensive care unit.World journal of nephrology · 2018Review
- Clinical characteristics of sepsis-induced acute kidney injury in patients undergoing continuous renal replacement therapy.Renal failure · 2018Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Continuous renal replacement therapy (CRRT) is one of the dialysis modalities for critically ill patients. Despite intensive dialysis care, a high mortality rate is found in these patients. Our objective was to investigate the factors associated with poor outcomes in these patients. We conducted a retrospective cohort study using the National Health Insurance Research Database. Records of critically ill patients who received CRRT between 2007 and 2011 were retrieved, and the patients were categorized into two groups: those with acute kidney injury (AKI) and those with history of end-stage renal disease (ESRD). Our primary and secondary outcomes were in-hospital mortality and long-term survival and non-renal recovery (long-term dialysis dependence), respectively, in the AKI group. We enrolled 15,453 patients, with 13,204 and 2249 in the AKI and ESRD groups, respectively. Overall, 66.5% patients died during hospitalization. In-hospital mortality did not differ significantly between groups (adjusted odds ratio, 0.93; 95% CI, 0.84-1.02). Age, chronic liver disease, and cancer history were identified as independent risk factors for in-hospital mortality in both groups. Hypertension was associated with higher risk of in-hospital mortality in patients with AKI. Age, coronary artery disease, and admission to the medical intensive care unit (MICU) were risk factors for long-term dialysis dependence in patients with AKI. Patients with AKI and ESRD have similarly poor outcomes after CRRT. Older age and presence of chronic liver disease and cancer were associated with higher mortality. Older age, presence of coronary artery disease, and admission to MICU were associated with lower renal recovery rate in patients with AKI.
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