Evidence map›Paper›PMID 28541646›Full record

Trial reportThe Journal of clinical psychiatry

Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) for Hoarding Disorder in Older Adults: A Randomized Clinical Trial.

Catherine R Ayers, Mary E Dozier, Elizabeth W Twamley, Sanjaya Saxena, Eric Granholm, Tina L Mayes, Julie Loebach Wetherell

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of clinical psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01227057 (Treatment of Late Life Compulsive Hoarding), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01227057 nacompletednot on this map

Treatment of Late Life Compulsive Hoarding

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2010 to 2015Enrolled58ConditionsCompulsive HoardingArmsCognitive Rehabilitation and Exposure Therapy for Compulsive Hoarding, Case Management
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Recent Advances in Research on Hoarding.Current psychiatry reports · 2019
    Review
  11. Article
  12. Article
  13. Predictors of treatment outcome and attrition in adults with hoarding disorder.Journal of obsessive-compulsive and related disorders · 2018
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Catherine R Ayers3350 La Jolla Village Drive, 116B, San Diego, CA 92161. cayers@ucsd.edu.
Mary E DozierSan Diego State University/University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA.
Elizabeth W TwamleyDepartment of Psychiatry, University of California, San Diego School of Medicine, San Diego, California, USA.
Sanjaya SaxenaDepartment of Psychiatry, University of California, San Diego School of Medicine, San Diego, California, USA.
Eric GranholmMental Health Care Line, VA San Diego Healthcare System, San Diego, California, USA.
Tina L MayesResearch Service, VA San Diego Healthcare System, San Diego, California, USA.
Julie Loebach WetherellMental Health Care Line, VA San Diego Healthcare System, San Diego, California, USA.
University of California, San Diego · USSan Diego State University · USVA San Diego Healthcare System · US

Funding

Cognitive Rehabilitation and Exposure Therapy for Veterans with Hoarding DisorderI01CX001149 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI AYERS, CATHERINE · 2016 to 2021
–
CSRD VA CDA-2-068-10SCSRD VA I01 CX001149
6 · The paper itself

Abstract

objectiveTo compare the efficacy of Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) with geriatric case management (CM) in a sample of older adults meeting DSM-5 diagnostic criteria for hoarding disorder (HD).

methodsFifty-eight older adults with HD were enrolled in a randomized controlled trial between December 2011 and March 2014. Thirty-one participants received CREST, and 27 participants received CM. Both interventions consisted of 26 individual sessions over a period of 6 months and included several home visits by the study therapists (CREST) or nurses (CM). The Saving Inventory-Revised (SI-R) and the UCLA Hoarding Severity Scale (UHSS) were the main outcome measures.

resultsParticipants in the CREST condition had significantly greater improvement on the SI-R than participants in the CM group (group × time interaction: β = 3.95, SE = 1.81, P = .029), with participants who completed the CREST condition averaging a 38% decrease in symptoms and participants who completed the CM condition averaging a 25% decrease in symptoms. In contrast, there was not a significant group × time interaction effect on the UHSS (β = 1.23, SE = 0.84, P = .144), although participants did report greater improvement in symptoms in the CREST condition (35%) than in the CM condition (24%). Treatment gains were maintained at 6-month follow-up.

conclusionsCREST appears to be an efficacious treatment compared to CM for older adults, but CM also showed meaningful benefits.

trial registrationClinicalTrials.gov identifier: NCT01227057​.

Indexed as

Hoarding DisorderHouse CallsAgedCognitionCognitive Behavioral TherapyDiagnostic and Statistical Manual of Mental DisordersFemaleGeriatric AssessmentHumansMalePsychiatric Status Rating ScalesSeverity of Illness IndexTreatment Outcome

Identifiers

PMID28541646
PMCPMC7295125
OpenAlexW2618015199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.