ArticleGenome biology and evolution2017
Genome-Wide SNP Analysis Reveals Distinct Origins of Trypanosoma evansi and Trypanosoma equiperdum.
Article in Genome biology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 53 citations in OpenAlex.
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- A strategic discovery roadmap towards high-quality leads and drug development candidates for kinetoplastid diseases. Part 2: from molecule to confirmed hit.The Journal of antimicrobial chemotherapy · 2026Review
- Effect of Parasitic Infections on Hematological Profile, Reproductive and Productive Performance in Equines.Animals : an open access journal from MDPI · 2025Review
- Hidden menace: Understanding the devastating consequences of dourine disease in horses.Open veterinary journal · 2025Review
- Mechanisms of life cycle simplification in African trypanosomes.Nature communications · 2024Article
- Article
- An Atlas of Surra in Spain: A Tool to Support Epidemiological Investigations and Disease Control.Animals : an open access journal from MDPI · 2024Article
- Molecular identification of new Trypanosoma evansi type non-A/B isolates from buffaloes and cattle in Indonesia.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2024Article
- European Inter-Laboratory Proficiency Test for Dourine Antibody Detection Using the Complement Fixation Test.Veterinary sciences · 2023Article
- Biochemical and genotyping analyses of camels (Camelus dromedaries) trypanosomiasis in North Africa.Scientific reports · 2023Article
- Molecular Analysis of Trypanosome Infections in Algerian Camels.Acta parasitologica · 2022Article
- In vitro anti-trypanosomal effect of ivermectin on Trypanosoma evansi by targeting multiple metabolic pathways.Tropical animal health and production · 2022Article
- Diagnosis of animal trypanosomoses: proper use of current tools and future prospects.Parasites & vectors · 2022Review
- Signatures of hybridization in Trypanosoma brucei.PLoS pathogens · 2022Article
- Development of a microsphere-based immunoassay for the serological diagnosis of equine trypanosomosis.Scientific reports · 2022Article
- rKOMICS: an R package for processing mitochondrial minicircle assemblies in population-scale genome projects.BMC bioinformatics · 2021Article
- MonomorphicMicrobial genomics · 2021Article
- Article
- Mitochondrial DNAs provide insight into trypanosome phylogeny and molecular evolution.BMC evolutionary biology · 2020Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trypanosomes cause a variety of diseases in man and domestic animals in Africa, Latin America, and Asia. In the Trypanozoon subgenus, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense cause human African trypanosomiasis, whereas Trypanosoma brucei brucei, Trypanosoma evansi, and Trypanosoma equiperdum are responsible for nagana, surra, and dourine in domestic animals, respectively. The genetic relationships between T. evansi and T. equiperdum and other Trypanozoon species remain unclear because the majority of phylogenetic analyses has been based on only a few genes. In this study, we have conducted a phylogenetic analysis based on genome-wide SNP analysis comprising 56 genomes from the Trypanozoon subgenus. Our data reveal that T. equiperdum has emerged at least once in Eastern Africa and T. evansi at two independent occasions in Western Africa. The genomes within the T. equiperdum and T. evansi monophyletic clusters show extremely little variation, probably due to the clonal spread linked to the independence from tsetse flies for their transmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.