ArticleJournal of biomedical optics2017
Handheld tunable focus confocal microscope utilizing a double-clad fiber coupler for in vivo imaging of oral epithelium.
Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Deep-learning endomicroscope with large field-of-view and depth-of-field for real-time in vivo imaging of epithelial cancer hallmarks.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Role of optical imaging in oral cancer and oral potentially malignant disorders: implications for oral submucous fibrosis.Frontiers in oral health · 2025Review
- Technologies for depth scanning in miniature optical imaging systems [Invited].Biomedical optics express · 2023Review
- In vivo microscopy as an adjunctive tool to guide detection, diagnosis, and treatment.Journal of biomedical optics · 2022Article
- Double-Clad Fiber-Based Multifunctional Biosensors and Multimodal Bioimaging Systems: Technology and Applications.Biosensors · 2022Review
- Enhanced detection of oral dysplasia by structured illumination fluorescence lifetime imaging microscopy.Scientific reports · 2021Article
- Algorithm to quantify nuclear features and confidence intervals for classification of oral neoplasia from high-resolution optical images.Journal of medical imaging (Bellingham, Wash.) · 2020Article
- Prospective evaluation of oral premalignant lesions using a multimodal imaging system: a pilot study.Head & neck · 2020Article
- In vivo imaging of cervical precancer using a low-cost and easy-to-use confocal microendoscope.Biomedical optics express · 2020Article
- Feasibility of a Video-Mosaicking Approach to Extend the Field-of-View For Reflectance Confocal Microscopy in the Oral Cavity In Vivo.Lasers in surgery and medicine · 2019Article
- Label-free in vivo pathology of human epithelia with a high-speed handheld dual-axis confocal microscope.Journal of biomedical optics · 2019Article
- Handheld line-scanned dual-axis confocal microscope with pistoned MEMS actuation for flat-field fluorescence imaging.Optics letters · 2019Article
- Noninvasive diagnostic adjuncts for the evaluation of potentially premalignant oral epithelial lesions: current limitations and future directions.Oral surgery, oral medicine, oral pathology and oral radiology · 2018Review
- Spectrally encoded coherence tomography and reflectometry: Simultaneous en face and cross-sectional imaging at 2 gigapixels per second.Journal of biophotonics · 2018Article
- Dual-axis confocal microscopy for point-of-care pathology.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
A reflectance confocal endomicroscope with double-clad fiber coupler and electrically tunable focus lens is applied to imaging of the oral mucosa. The instrument is designed to be lightweight and robust for clinical use. The tunable lens allows axial scanning through > 250 ?? ? m in the epithelium when the probe tip is placed in contact with tissue. Images are acquired at 6.6 frames per second with a field of view diameter up to 850 ?? ? m . In vivo imaging of a wide range of normal sites in the oral cavity demonstrates the accessibility of the handheld probe. In vivo imaging of clinical lesions diagnosed as inflammation and dysplasia illustrates the ability of reflectance confocal endomicroscopy to image cellular changes associated with pathology.
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Registered trials
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