Evidence map›Paper›PMID 28541410›Full record

ArticleAmerican journal of epidemiology2017

Contribution of Socioeconomic Status at 3 Life-Course Periods to Late-Life Memory Function and Decline: Early and Late Predictors of Dementia Risk.

Jessica R Marden, Eric J Tchetgen Tchetgen, Ichiro Kawachi, M Maria Glymour

Abstract read
In one paragraph

Article in American journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 168 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

168 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effect of a cash transfer intervention on memory decline and dementia probability in older adults in rural South Africa.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. [Modifiable risk and protective factors for dementia: an overview of established and emerging evidence].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
    Review
  11. Observational
  12. Article
  13. Considerations in Alzheimer's Disease in Women.Current neurology and neuroscience reports · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Lifecourse socioeconomic status and subjective cognitive decline among diverse older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  18. Article
  19. Article
  20. Article

108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessica R Marden
Eric J Tchetgen Tchetgen
Ichiro Kawachi
M Maria Glymour

Funding

Training Program in Psychiatric Genetics and Translational ResearchT32MH017119 · NIMH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KARESTAN C KOENEN, Jukka-Pekka Onnela · 1985 to 2026
$8.9M
Training in Neurostatistics and NeuroepidemiologyT32NS048005 · NINDS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ONNELA, JUKKA-PEKKA · 2004 to 2018
$3.2M
Identification and Inference for Longitudinal Causal Mediation Analysis in HIVR01AI104459 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI SHPITSER, ILYA, VANDERWEELE, TYLER · 2013 to 2017
$2.0M
NIAID NIH HHS R01 AI104459NIMH NIH HHS T32 MH017119NINDS NIH HHS T32 NS048005
6 · The paper itself

Abstract

Both early life and adult socioeconomic status (SES) predict late-life level of memory; however, evidence is mixed on the relationship between SES and rate of memory decline. Further, the relative importance of different life-course periods for rate of late-life memory decline has not been evaluated. We examined associations between life-course SES and late-life memory function and decline. Health and Retirement Study participants (n = 10,781) were interviewed biennially from 1998-2012 (United States). SES measurements for childhood (composite score including parents' educational attainment), early adulthood (high-school or college completion), and older adulthood (income, mean age 66 years) were all dichotomized. Word-list memory was modeled via inverse-probability weighted longitudinal models accounting for differential attrition, survival, and time-varying confounding, with nonrespondents retained via proxy assessments. Compared to low SES at all 3 points (referent), stable, high SES predicted the best memory function and slowest decline. High-school completion had the largest estimated effect on memory (β = 0.19; 95% confidence interval: 0.15, 0.22), but high late-life income had the largest estimated benefit for slowing declines (for 10-year memory change, β = 0.35; 95% confidence interval: 0.24, 0.46). Both early and late-life interventions are potentially relevant for reducing dementia risk by improving memory function or slowing decline.

Indexed as

Educational StatusSocial ClassAgedAged, 80 and overDementiaFemaleHumansIncomeMaleMemoryMemory DisordersRisk FactorsUnited Statescognitioncognitive declinedeclineeducationincomememorymemory declinesocioeconomic status

Identifiers

PMID28541410
PMCPMC5859987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.