ArticleJournal of perinatology : official journal of the California Perinatal Association2017
Cerebrospinal fluid procalcitonin as a biomarker of bacterial meningitis in neonates.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Cerebrospinal Procalcitonin for Diagnosing Meningitis in Infants Less Than 90 Days: A Systematic Review and Meta-analysis.Indian pediatrics · 2025Pooled it
- Early prognostic value of repeat CSF parameter measurements in neonatal bacterial meningitis following initial antimicrobial therapy.Italian journal of pediatrics · 2025Article
- Diagnostic Utility of Procalcitonin and Lactate Determination in Cerebrospinal Fluid for the Diagnosis of Neonatal Meningitis.Journal of clinical medicine · 2025Article
- The Diagnostic Utility of Cerebrospinal Fluid Procalcitonin for Acute Bacterial Meningitis and Ventriculitis in Children: A Multicenter Prospective Study.Acta medica Philippina · 2025Article
- Granulocytes in cerebrospinal fluid of adults suspected of a central nervous system infection: a prospective study of diagnostic accuracy.Infection · 2024Article
- High-throughput sequencing unravels the cell heterogeneity of cerebrospinal fluid in the bacterial meningitis of children.Frontiers in immunology · 2022Article
- NLRP3 in the Cerebrospinal Fluid as a Potential Biomarker for the Diagnosis and Prognosis of Community-Acquired Bacterial Meningitis in Adults.Frontiers in cellular and infection microbiology · 2021Article
- An improved clinical prediction rule for identifying neonatal bacterial meningitis: a multicenter cohort study.Translational pediatrics · 2021Article
- Value of lipocalin 2 as a potential biomarker for bacterial meningitis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of the study was to study the performance of cerebrospinal fluid (CSF) procalcitonin as a marker for bacterial meningitis in neonates, and to determine its optimal 'cutoff' in CSF that can be called significant for the diagnosis. STUDY
designNeonates qualifying for lumbar puncture were prospectively studied. Procalcitonin and established CSF parameters were recorded.
resultsAt a cut-off value of 0.33 ng ml
conclusionsProcalcitonin measurement has diagnostic efficiency similar to the established CSF markers. Routine assessment of procalcitonin in clean non-contaminated CSF may not yield additional information, but it may have clinical utility in situations where diagnosis of meningitis is in dilemma, as in the case of blood contamination of CSF in traumatic lumbar punctures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.