Evidence map›Paper›PMID 28541013›Full record

ArticleThe New England journal of medicine2017

Gene Therapy in a Patient with Sickle Cell Disease.

Mohsin Badat, James Davies

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in The New England journal of medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Chronic organ failure in adult sickle cell disease.Hematology. American Society of Hematology. Education Program · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mohsin BadatMedical Research Council Weatherall Institute of Molecular Medicine, Oxford, United Kingdom
James DaviesMedical Research Council Weatherall Institute of Molecular Medicine, Oxford, United Kingdom

Funding

Medical Research Council G1000801Medical Research Council MC_PC_15069Medical Research Council MC_U137961144Medical Research Council MC_U137961145Medical Research Council MC_UU_00016/4Medical Research Council MC_UU_12009/4Medical Research Council MR/P019633/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle CellGenetic TherapyHumans

Identifiers

PMID28541013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.