ArticleInternational journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group2018
Computation of ultimate SAR amplification factors for radiofrequency hyperthermia in non-uniform body models: impact of frequency and tumour location.
Article in International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 26 citations in OpenAlex.
- An Open-Source Software Toolbox for Rapid Radiofrequency Coil Design and Evaluation in MRI.Magnetic resonance in medicine · 2026Article
- An Optimization Framework for the Design of Radiofrequency Coils for Magnetic Resonance Imaging.bioRxiv : the preprint server for biology · 2025Article
- Helmet Radio Frequency Phased Array Applicators Enhance Thermal Magnetic Resonance of Brain Tumors.Bioengineering (Basel, Switzerland) · 2024Article
- Tier-based formalism for safety assessment of custom-built radio-frequency transmit coils.NMR in biomedicine · 2023Article
- Novel Numerical Basis Sets for Electromagnetic Field Expansion in Arbitrary Inhomogeneous Objects.IEEE transactions on antennas and propagation · 2022Article
- Microwave Hyperthermia of Brain Tumors: A 2D Assessment Parametric Numerical Study.Sensors (Basel, Switzerland) · 2022Article
- SAR and temperature distributions in a database of realistic human models for 7 T cardiac imaging.NMR in biomedicine · 2021Article
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- Multi-Channel RF Supervision Module for Thermal Magnetic Resonance Based Cancer Therapy.Cancers · 2021Article
- A formalism to investigate the optimal transmit efficiency in radiofrequency shimming.NMR in biomedicine · 2020Article
- Article
- Solving the Time- and Frequency-Multiplexed Problem of Constrained Radiofrequency Induced Hyperthermia.Cancers · 2020Article
- Radiofrequency applicator concepts for thermal magnetic resonance of brain tumors at 297 MHz (7.0 Tesla).International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2020Article
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
purposeWe introduce a method for calculation of the ultimate specific absorption rate (SAR) amplification factors (uSAF) in non-uniform body models. The uSAF is the greatest possible SAF achievable by any hyperthermia (HT) phased array for a given frequency, body model and target heating volume.
methodsFirst, we generate a basis-set of solutions to Maxwell's equations inside the body model. We place a large number of electric and magnetic dipoles around the body model and excite them with random amplitudes and phases. We then compute the electric fields created in the body model by these excitations using an ultra-fast volume integral solver called MARIE. We express the field pattern that maximises the SAF in the target tumour as a linear combination of these basis fields and optimise the combination weights so as to maximise SAF (concave problem). We compute the uSAFs in the Duke body models at 10 frequencies in the 20-900 MHz range and for twelve 3 cm-diameter tumours located at various depths in the head and neck.
resultsFor both shallow and deep tumours, the frequency yielding the greatest uSAF was ∼900 MHz. Since this is the greatest frequency that we simulated, we hypothesise that the globally optimal frequency is actually greater.
conclusionsThe uSAFs computed in this work are very large (40-100 for shallow tumours and 4-17 for deep tumours), indicating that there is a large room for improvement of the current state-of-the-art head and neck HT devices.
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