ReviewJournal of neuro-oncology2017
Fatigue in patients with low grade glioma: systematic evaluation of assessment and prevalence.
Review in Journal of neuro-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Interventions for the management of fatigue in adults with a primary brain tumour.The Cochrane database of systematic reviews · 2022Pooled it
- Isocitrate Dehydrogenase, Patient-Reported Outcomes, and Cognitive Functioning of Glioma Patients: a Systematic Review.Current oncology reports · 2020Pooled it
- Bayesian adaptive randomized trial of blended cognitive behavioral therapy for severe fatigue in stable diffuse glioma.Neuro-oncology · 2026Trial
- eHealth cognitive rehabilitation for brain tumor patients: results of a randomized controlled trial.Journal of neuro-oncology · 2021Trial
- Copenhagen longitudinal study on quality of life in a young adult population with gliomas.Acta neurochirurgica · 2026Article
- "Such a different type of tiredness": people with brain tumour, their caregivers', and healthcare professionals' qualitative perceptions of cancer-related fatigue.Journal of cancer survivorship : research and practice · 2026Article
- Heterogeneous trajectory of cancer-related fatigue and its associated factors in patients with glioma during the perioperative period: a prospective longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- The Impact of Sociodemographic Disparities on Health-Related Quality of Life for Adults with Gliomas.Cancers · 2026Review
- Multiscale network perspectives on glioma: from tumour biology to symptoms, survival and treatment.Nature reviews. Neurology · 2026Review
- Distinguishing Mental From Physical Fatigue in Patients With Low-Grade Glioma.Psycho-oncology · 2025Article
- Co-designing a web-based intervention (RESTORE) to support self-management of cancer-related fatigue in people living with a brain tumour.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Mental fatigue and cognitive functioning in patients presenting with non-enhancing gliomas.Acta neurochirurgica · 2025Article
- Symptom management in isocitrate dehydrogenase mutant glioma.Neuro-oncology practice · 2025Review
- Health-related quality of life in 62 patients with diffuse low-grade glioma during a non-therapeutic and progression-free phase: a cross-sectional study.Journal of neuro-oncology · 2025Article
- Case report: Pseudoprogression mimicking neoplastic recurrence three months after completion of proton beam therapy for an IDH-mutant astrocytoma CNS WHO grade 3.Frontiers in oncology · 2025Article
- Global health status and fatigue score in isocitrate dehydrogenase-mutant diffuse glioma grades 2 and 3: A longitudinal population-based study from surgery to 12-month follow-up.Neuro-oncology practice · 2024Article
- Understanding the association between fatigue and neurocognitive functioning in patients with glioma: A cross-sectional multinational study.Neuro-oncology practice · 2024Article
- Circulating Brain Injury Biomarkers: A Novel Method for Quantification of the Impact on the Brain After Tumor Surgery.Neurosurgery · 2023Article
- Experiences of work for people living with a grade 2/3 oligodendroglioma: a qualitative analysis within the Ways Ahead study.BMJ open · 2023Article
- Lifestyle coaching is feasible in fatigued brain tumor patients: A phase I/feasibility, multi-center, mixed-methods randomized controlled trial.Neuro-oncology practice · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatigue is the most prevalent and disabling symptom in cancer patients. Yet, scientific literature on this topic is scarce and reports disparate results. This study systematically reviews how fatigue is assessed in patients with low-grade glioma and evaluates its prevalence in LGG patients. A systematic literature search was performed in PubMed, Embase and PsychINFO for articles reporting on fatigue in patients with LGG. Two reviewers independently extracted data from selected articles. Inclusion criteria were: (1) patients with suspected or confirmed LGG; (2) fatigue was assessed as primary or secondary outcome measure; (3) age≥ 18 years; (4) full-length article written in English or Dutch. In total, 19 articles were selected, including 971 patients. Seven self-assessment instruments were identified. Prevalence rates ranged from 39 to 77%. Fatigue was found to be a common side effect of treatment. The prevalence rates ranged from 20 to 76% when fatigue was reported as a mild or moderate side effect and fatigue was prevalent in 4% when reported as a severe side effect. Fatigue is a common problem in LGG patients that warrants more therapeutic and scientific attention. Gaining deeper insight in the underlying mechanisms of fatigue is essential in targeting therapy to individual patients.
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