ArticleMolecular imaging and biology2018
Changes in Tumor Biology During Chemoradiation of Cervix Cancer Assessed by Multiparametric MRI and Hypoxia PET.
Article in Molecular imaging and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Multi-parametric MRI (mpMRI) for treatment response assessment of radiation therapy.Medical physics · 2022Article
- The clinical utility of imaging methods used to measure hypoxia in cervical cancer.The British journal of radiology · 2020Review
- The 2019 World Molecular Imaging Congress (WMIC) and Molecular Imaging and Biology (MIB) Awards.Molecular imaging and biology · 2020Article
- The rationale for MR-only treatment planning for external radiotherapy.Clinical and translational radiation oncology · 2019Review
- Sequential [Contrast media & molecular imaging · 2019Article
- Longitudinal PET imaging of tumor hypoxia during the course of radiotherapy.European journal of nuclear medicine and molecular imaging · 2018Review
- Hypoxia Imaging and Biological Evaluation of the Radiosensitizing Effect of Oleanolic Acid.BioMed research international · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeImaging biomarkers assessed with magnetic resonance imaging (MRI) and/or positron emission tomography (PET) enable non-invasive tumor characterization in cervix cancer patients. We investigated the spatio-temporal stability of hypoxia, perfusion, and the cell density of tumors over time by repetitive imaging prior to, during, and after radio-chemotherapy. PROCEDURES: Thirteen patients were included in this prospective study. The imaging protocol included the following: [
resultsMedian tumor ADCs (in ×10
conclusionsLongitudinal mp-MR and PET imaging enables the in vivo tumor characterization over time. While perfusion and cell density decreased, there was a non-uniform change of hypoxia observed during radiotherapy. To assess the potential impact with regard to more personalized treatment approaches, hypoxia imaging-based dose painting for cervix cancer requires further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.