Evidence map›Paper›PMID 28540416›Full record

ArticleRheumatology international2017

Breastfeeding initiation, duration, and reasons for weaning in patients with systemic lupus erythematosus.

Magdalena Acevedo, Julia Pretini, Marina Micelli, Gabriel Sequeira, Eduardo Kerzberg

Abstract read
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In one paragraph

Article in Rheumatology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Drugs in Lactation.Pharmaceutical research · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Magdalena AcevedoServicio de Reumatología, Hospital J. M. Ramos Mejía, Urquiza 609, (ZIP 1221), Ciudad Autónoma de Buenos Aires, Argentina.
Julia PretiniServicio de Reumatología, Hospital J. M. Ramos Mejía, Urquiza 609, (ZIP 1221), Ciudad Autónoma de Buenos Aires, Argentina.
Marina MicelliServicio de Reumatología, Hospital J. M. Ramos Mejía, Urquiza 609, (ZIP 1221), Ciudad Autónoma de Buenos Aires, Argentina.
Gabriel SequeiraServicio de Reumatología, Hospital J. M. Ramos Mejía, Urquiza 609, (ZIP 1221), Ciudad Autónoma de Buenos Aires, Argentina. gabriel.sequeira@live.com.ar.
Eduardo KerzbergServicio de Reumatología, Hospital J. M. Ramos Mejía, Urquiza 609, (ZIP 1221), Ciudad Autónoma de Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess breastfeeding in patients with systemic lupus erythematosus (SLE), a cross-sectional study of patients with SLE compared to a non-SLE sample was performed. Patients who had pregnancies subsequent to their diagnosis of SLE and who were followed up in the hospital were interviewed. The group of non-SLE mothers consisted of patients who had no known rheumatic disease at the time of their pregnancy, and who were approached at the hospital paediatrics service waiting room. Thirty-six pregnancies in 31 patients with SLE and the same number of non-SLE mothers were studied. The number of SLE patients who did not initiate breastfeeding was higher than that of non-SLE mothers (19.4 vs 5.6%, respectively; p 0.07). The average duration of breastfeeding in SLE patients was 6 months (SD 6 months) versus 12 months (SD 8 months) in non-SLE mothers (log rank p: 0.003). Fifty-three percent of the non-SLE mothers indicated no particular reason for weaning, and considered that they had nursed their children a suitable amount of time. Conversely, SLE patients often set weaning in motion on the grounds that they had been placed on medication (41%). However, when the treatment was analysed, in 6 out of 12 cases, it consisted of low doses of either corticosteroids or hydroxychloroquine. Patients with SLE showed reduced rates of initiating breastfeeding. They also showed reduced duration of breastfeeding, and the reason for cessation was frequently cited to be therapies which were actually of low risk. Breastfeeding duration could be optimised by improving the level of information provided to patients.

Indexed as

Breast FeedingWeaningAdrenal Cortex HormonesAdultAntirheumatic AgentsCross-Sectional StudiesFemaleHumansHydroxychloroquineKaplan-Meier EstimateLupus Erythematosus, SystemicRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsYoung AdultAdrenal Cortex HormonesAntirheumatic AgentsHydroxychloroquineBreastfeedingHydroxychloroquineSystemic lupus erythematosusWeaning

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.