Evidence map›Paper›PMID 28540272›Full record

ArticleIranian journal of public health2017

Evaluation of the Effects of Local Application of Thyme Honey in Open Cutaneous Wound Healing.

Nasrin Takzaree, Gholamreza Hassanzadeh, Mohammad Reza Rouini, Azadeh Manayi, Abbas Hadjiakhondi, Masoumeh Majidi Zolbin

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Iranian journal of public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07358494 (Effect of Diluted Thyme Honey On Dry Mouth In Intensive Care Unit Patients Exposed to Oxygen Flow Therapy), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07358494 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Diluted Thyme Honey On Dry Mouth In Intensive Care Unit Patients Exposed to Oxygen Flow Therapy: A Randomized Controlled Study

TypeinterventionalSponsorEsra Yaprak GokturkRan2022 to 2022Enrolled64ConditionsNursing CareArmsdiluted thyme honey arm, Mouth wash
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Wound Healing Properties of Selected Natural Products.International journal of environmental research and public health · 2018
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nasrin TakzareeDept. of Anatomy & Histology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Gholamreza HassanzadehDept. of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Reza RouiniMedicinal Plants Research Center, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Azadeh ManayiMedicinal Plants Research Center, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Abbas HadjiakhondiMedicinal Plants Research Center, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Masoumeh Majidi ZolbinDept. of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinicians have been searching for ways to obtain "super normal" wound healing. Honey is a traditional remedy for the treatment of infected wounds. We aimed to evaluate the wound contraction and antibacterial properties of locally produced Thyme honey on managing full-thickness wounds in vivo.

methodsThis experimental study was conducted in 2015, in Department of Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran on 54 adult male Wistar rats weighing 200-250 gr, and ages of 3-4 months. A square 1.5*1.5 wound was made on the back of the neck. The rats were divided into control and two experimental groups. Additionally, the control and experimental groups were separated into three subgroups corresponding to 4, 7, and 14 d of study. The control group did not receive any treatment. For histological studies, samples were taken from the wound and adjacent skin. This tissue was examined using histological staining (H&E). Wound surface and wound healing were evaluated. Data were analyzed by using one-way ANOVA with post hoc Tukey test and (

resultsThe macroscopic and microscopic evaluations showed that the percentage of wound healing on different days in the control and experimental groups were significant (

conclusionUsing honey twice a day on open wounds will accelerate the healing process.

Indexed as

HoneyOpen cutaneous woundRatWound healing

Identifiers

PMID28540272
PMCPMC5439045
OpenAlexW2608597049

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.