ArticleTranslational andrology and urology2017
Liquid biopsies for bladder cancer.
Article in Translational andrology and urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Diffusion-weighted MRI to determine response and long-term clinical outcomes in muscle-invasive bladder cancer following neoadjuvant chemotherapy.Frontiers in oncology · 2022Article
- Trends in urine biomarker discovery for urothelial bladder cancer: DNA, RNA, or protein?Translational andrology and urology · 2021Review
- Urinary Cell-Free DNA in Bladder Cancer Detection.Diagnostics (Basel, Switzerland) · 2021Review
- Low-Coverage Sequencing of Urine Sediment DNA for Detection of Copy Number Aberrations in Bladder Cancer.Cancer management and research · 2021Article
- Detection of bladder cancer using urinary cell-free DNA and cellular DNA.Clinical and translational medicine · 2020Article
- Patients choose certainty over burden in bladder cancer surveillance.World journal of urology · 2019Article
- Targeted deep sequencing of urothelial bladder cancers and associated urinary DNA: a 23-gene panel with utility for non-invasive diagnosis and risk stratification.BJU international · 2019Article
- Massively parallel sequencing of urinary DNA-the dawn of non-invasive bladder cancer detection and surveillance?Translational cancer research · 2019Article
- New method to preserve the original proportion and integrity of urinary cell-free DNA.Journal of clinical laboratory analysis · 2019Article
- Advances in liquid biopsy on-chip for cancer management: Technologies, biomarkers, and clinical analysis.Critical reviews in clinical laboratory sciences · 2018Review
- Red patches during bladder cancer surveillance: to biopsy or not to biopsy?Translational andrology and urology · 2018Article
- Urinary Markers in Bladder Cancer: An Update.Frontiers in oncology · 2018Review
- Urinary exosomal expression of long non-coding RNAs as diagnostic marker in bladder cancer.Cancer management and research · 2018Article
- Multiplex Cell-Free DNA Reference Materials for Quality Control of Next-Generation Sequencing-BasedJournal of Cancer · 2018Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of accurate urinary biomarkers for the non-invasive detection of urothelial bladder cancer (UBC) could transform patient pathways by reducing reliance on cystoscopy, and the identification of highly prognostic (or even predictive) biomarkers could better guide patient management. A number of approaches are being utilised to address these challenges in both urinary- and plasma-borne tumour DNA (tDNA), so-called "liquid biopsies". Next generation sequencing (NGS) and droplet digital PCR (ddPCR) allow detection of very low levels of such tDNA amongst a large excess of non-tumour DNA, the former permitting large mutation panels to be assessed and the latter potentially identifying ultrarare mutant alleles yet restricted for multiplexing. Christensen
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.