Evidence map›Paper›PMID 28540209›Full record

ReviewCardiovascular diagnosis and therapy2017

Myocardial blood flow quantification for evaluation of coronary artery disease by computed tomography.

Filippo Cademartiri, Sara Seitun, Alberto Clemente, Ludovico La Grutta, Patrizia Toia, Giuseppe Runza, Massimo Midiri, Erica Maffei

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Cardiovascular diagnosis and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06886958 (Spectral CT Protocol Optimization for Atherosclerotic Plaque CharacterizatION), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06886958 active not recruitingnot on this mapstarted 2023, after this paper: background citation

Spectral CT Protocol Optimization for Atherosclerotic Plaque CharacterizatION

TypeobservationalSponsorIRCCS SYNLAB SDNRan2023 to 2025Enrolled100ConditionsAtherosclerotic Disease
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Coronary microvascular dysfunction: a narrative review.Cardiovascular diagnosis and therapy · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Cardiac CT perfusion and FFRCardiovascular diagnosis and therapy · 2020
    Review
  14. Review
  15. Review
  16. Article
  17. Prognostic value of cardiac CT.La Radiologia medica · 2020
    Review
  18. Dual-energy CT and coronary imaging.Cardiovascular diagnosis and therapy · 2020
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Filippo CademartiriDepartment of Radiology, Montreal Heart Institute, Université de Montreal, Montreal, Canada.
Sara SeitunDepartment of Radiology, IRCCS AOU San Martino-IST, Genoa, Italy.
Alberto ClementeDepartment of Radiology, Fondazione Toscana Gabriele Monasterio, Pisa and Massa, Italy.
Ludovico La GruttaDepartment of Radiology, University of Palermo, Palermo, Italy.
Patrizia ToiaDepartment of Radiology, University of Palermo, Palermo, Italy.
Giuseppe RunzaDepartment of Radiology, P.O. Umberto I, Azienda Sanitaria Provinciale 8, Siracusa, Italy.
Massimo MidiriDepartment of Radiology, University of Palermo, Palermo, Italy.
Erica MaffeiDepartment of Radiology, Montreal Heart Institute, Université de Montreal, Montreal, Canada.
University of Palermo · ITFondazione Toscana Gabriele Monasterio · ITMontreal Heart Institute · CAOspedale Policlinico San Martino · ITUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last decade coronary computed tomography angiography (CTA) has become the preeminent non-invasive imaging modality to detect coronary artery disease (CAD) with high accuracy. However, CTA has a limited value in assessing the hemodynamic significance of a given stenosis due to a modest specificity and positive predictive value. In recent years, different CT techniques for detecting myocardial ischemia have emerged, such as CT-derived fractional flow reserve (FFR-CT), transluminal attenuation gradient (TAG), and myocardial CT perfusion (CTP) imaging. Myocardial CTP imaging can be performed with a single static scan during first pass of the contrast agent, with monoenergetic or dual-energy acquisition, or as a dynamic, time-resolved scan during stress by using coronary vasodilator agents (adenosine, dipyridamole, or regadenoson). A number of CTP techniques are available, which can assess myocardial perfusion in both a qualitative, semi-quantitative or quantitative manner. Once used primarily as research tools, these modalities are increasingly being used in routine clinical practice. All these techniques offer the substantial advantage of combining anatomical and functional evaluation of flow-limiting coronary stenosis in the same examination that would be beneficial for clinical decision-making. This review focuses on the state-of the-art and future trends of these evolving imaging modalities in the field of cardiology for the physiologic assessments of CAD.

Indexed as

Cardiac computed tomographycoronary artery disease (CAD)myocardial blood flow quantificationmyocardial perfusion imagingstress imaging

Identifiers

PMID28540209
PMCPMC5422837
OpenAlexW2611636720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.