Evidence map›Paper›PMID 28540205›Full record

ArticleWorld journal of nephrology2017

Clinicopathological spectrum of snake bite-induced acute kidney injury from India.

Sanjay Vikrant, Ajay Jaryal, Anupam Parashar

Open access · hybridAbstract read
In one paragraph

Article in World journal of nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Eburicoic Acid fromJournal of inflammation research · 2026
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  4. Masked peril: acute kidney injury in snakebite victims.Pediatric nephrology (Berlin, Germany) · 2025
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  10. Article
  11. Snake bite associated with acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2021
    Review
  12. Article
  13. Scrotal necrosis after cobra (Urology case reports · 2021
    Article
  14. Erythrocyte haemotoxicity profiling of snake venom toxins after nanofractionation.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2021
    Article
  15. Chronic kidney failure following lancehead bite envenoming: a clinical report from the Amazon region.The journal of venomous animals and toxins including tropical diseases · 2020
    Article
  16. Acute kidney failure following severe viper envenomation: clinical, biological and ultrasonographic aspects.The journal of venomous animals and toxins including tropical diseases · 2020
    Article
  17. Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Sanjay VikrantSanjay Vikrant, Ajay Jaryal, Department of Nephrology, Indira Gandhi Medical College, Himachal Pradesh, Shimla 171001, India.
Ajay JaryalSanjay Vikrant, Ajay Jaryal, Department of Nephrology, Indira Gandhi Medical College, Himachal Pradesh, Shimla 171001, India.
Anupam ParasharSanjay Vikrant, Ajay Jaryal, Department of Nephrology, Indira Gandhi Medical College, Himachal Pradesh, Shimla 171001, India.
Indira Gandhi Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the clinico-pathological spectrum of snake bite-induced acute kidney injury (AKI).

methodsA retrospective study of patients admitted at Indira Gandhi Medical College Hospital, Shimla with snake bite-induced AKI from July 2003 to June 2016. Medical records were evaluated for patient's information on demographic, clinical characteristics, complications and outcome. Outcomes of duration of hospital stay, requirement for intensive care unit support, treatment with dialysis, survival and mortality were analyzed. The survival and non survival groups were compared to see the difference in the demographic factors, clinical characteristics, laboratory results, and complications. In patients subjected to kidney biopsy, the findings of histopathological examination of the kidney biopsies were also analyzed.

resultsOne hundred and twenty-one patients were diagnosed with snake bite-induced AKI. Mean age was 42.2 ± 15.1 years and majority (58%) were women. Clinical details were available in 88 patients. The mean duration of arrival at hospital was 3.4 ± 3.7 d with a range of 1 to 30 d. Eighty percent had oliguria and 55% had history of having passed red or brown colored urine. Coagulation defect was seen in 89% patients. The hematological and biochemical laboratory abnormalities were: Anemia (80.7%), leukocytosis (75%), thrombocytopenia (47.7%), hyperkalemia (25%), severe metabolic acidosis (39.8%), hepatic dysfunction (40.9%), hemolysis (85.2%) and rhabdomyolysis (68.2%). Main complications were: Gastrointestinal bleed (12.5%), seizure/encephalopathy (10.2%), hypertension, pneumonia/acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (9.1% each), hypotension and multi organ failure (MOF) (4.5% each). Eighty-two percent patients required renal replacement therapy. One hundred and ten (90.9%) patient survived and 11 (9.1%) patients died. As compared to the survival group, the white blood cell count (

conclusionAKI due to snake bite is severe and a high proportion requires renal replacement therapy. On renal histology ATN and AIN are common, RCN is rare.

Indexed as

Acute interstitial nephritisAcute kidney injuryAcute tubular necrosisEnvenomationHemolysisRenal cortical necrosisRhabdomyolysisSnake bite

Identifiers

PMID28540205
PMCPMC5424437
OpenAlexW2610305549

What OpenQuestion holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.