ReviewBasic and clinical neuroscience
The Prevalence of Restless Legs Syndrome in Patients Undergoing Hemodialysis: A Systematic Review and Meta-analysis Study.
Review in Basic and clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Prevalence of restless legs syndrome in Pakistan: a systematic review and meta-analysis across diverse study populations.BMC neurology · 2026Pooled it
- Sleep disturbances in adults with chronic kidney disease: an umbrella review.Journal of nephrology · 2025Pooled it
- Global prevalence of restless legs syndrome among hemodialysis patients: A systematic review and meta-analysis.Brain and behavior · 2024Pooled it
- Evaluation of emotional dysregulation in patients with restless legs syndrome.Sleep and biological rhythms · 2023Article
- Leg restlessness and hyperparathyroidism in Parkinson's disease, a further clue to RLS pathogenesis?Frontiers in neurology · 2023Article
- Association of quality of life, anxiety, and depression with restless leg syndrome in the hemodialysis patients.BMC research notes · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRestless legs syndrome is a sensory-motor disorder that causes sleep disorder. The syndrome in patients undergoing hemodialysis associates with depression, sleep deprivation, performance disorder, day fatigue, excessive daytime sleepiness, stress, anxiety, and higher risk of cardiovascular diseases. The objective of this systematic meta-analysis study was to estimate prevalence of restless legs syndrome in patients undergoing hemodialysis.
methodsTwenty-six relevant articles published between 2000 and 2015 indexed in Iranian (MagIran and IranMedex) and international databases (SID, Google Scholar, ScienceDirect, PubMed, Pre Quest, and Scopus) were selected. Data analysis was carried out through meta-analysis (random effect model) and heterogeneity of the studies was determined using I2 index. The obtained data were analyzed in STAT (11.2).
resultsPrevalence of the syndrome according to the found articles was 50% (95% CI: 38-61) in Iranian and 30% (95% CI:23-37) in international databases. There was an ascending trend of prevalence of the syndrome corresponding to the publication year of the articles (P=0.419), while the trend based on age of the patients was descending (P=0.604). However, the variations were not significant.
conclusionGiven the high prevalence and considerable effects of restless legs syndrome on patients undergoing hemodialysis, it is recommended that these patients be screened for the syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.