Evidence map›Paper›PMID 28539979›Full record

ArticleDiabetology & metabolic syndrome2017

Association of metabolic syndrome and electrocardiographic markers of subclinical cardiovascular disease.

Theodora W Elffers, Renée de Mutsert, Hildo J Lamb, Arie C Maan, Peter W Macfarlane, Ko Willems van Dijk, Frits R Rosendaal, J Wouter Jukema, Stella Trompet

Open access · goldAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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  6. The association of metabolic syndrome and QRS|T angle in US adults (NHANES III).Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Theodora W ElffersDepartment of Clinical Epidemiology, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands.
Renée de MutsertDepartment of Clinical Epidemiology, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands.
Hildo J LambDepartment of Radiology, Leiden University Medical Center, 2300RC Leiden, The Netherlands.
Arie C MaanDepartment of Cardiology, Leiden University Medical Center, 2300RC Leiden, The Netherlands.
Peter W MacfarlaneInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Ko Willems van DijkDepartment of Human Genetics, Leiden University Medical Center, 2300RC Leiden, The Netherlands.
Frits R RosendaalDepartment of Clinical Epidemiology, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands.
J Wouter JukemaDepartment of Cardiology, Leiden University Medical Center, 2300RC Leiden, The Netherlands.
Stella TrompetDepartment of Cardiology, Leiden University Medical Center, 2300RC Leiden, The Netherlands.
Leiden University Medical Center · NLUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe metabolic syndrome (MetS) and its components are well-established risk factors for cardiovascular diseases (CVD). It is inconclusive whether MetS and MetS score are associated with electrocardiographic markers of subclinical CVD, therefore we investigated this in a population without pre-existing CVD.

methodsWe performed a cross-sectional analysis in the Netherlands Epidemiology of Obesity study, a population-based cohort including 6671 participants aged 45-65. We excluded participants with pre-existing CVD (n = 499) or missing MetS components (n = 58). MetS was defined based on a modified definition of Adult Treatment Panel III. Subclinical CVD parameters were determined with 12-lead ECGs. MetS score was defined as number of abnormal MetS components and obesity as Body Mass Index (BMI) ≥30 kg/m

resultsOur study population (n = 6114) had a mean (SD) BMI of 26.3 (4.4) kg/m

conclusionsMetabolic syndrome score and its individual components, in particular abdominal obesity, are associated with ECG markers of subclinical CVD, showing the importance of limiting the amount of MetS components in both obese and non-obese persons.

Indexed as

Cardiovascular diseaseMetabolic syndromeObesity

Identifiers

PMID28539979
PMCPMC5441065
OpenAlexW2618938853

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.