ArticlePsychiatry investigation2017
Disrupted Control Network Connectivity in Abstinent Patients with Alcohol Dependence.
Article in Psychiatry investigation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Relating Functional Connectivity and Alcohol Use Disorder: A Systematic Review and Derivation of Relevance Maps for Regions and Connections.Human brain mapping · 2025Pooled it
- Graph Theoretical Analysis of Brain Structural Connectivity in Patients with Alcohol Dependence.Experimental neurobiology · 2023Article
- Preliminary evidence for changes in frontoparietal network connectivity in the early abstinence period in alcohol use disorder: a longitudinal resting-state functional magnetic resonance imaging study.Frontiers in psychiatry · 2023Article
- Neural mechanisms underlying empathy during alcohol abstinence: evidence from connectome-based predictive modeling.Brain imaging and behavior · 2022Article
- Binge drinking is associated with altered resting state functional connectivity of reward-salience and top down control networks.Brain imaging and behavior · 2020Article
- Leveraging Neural Networks in Preclinical Alcohol Research.Brain sciences · 2020Review
- Random Forest Classification of Alcohol Use Disorder Using EEG Source Functional Connectivity, Neuropsychological Functioning, and Impulsivity Measures.Behavioral sciences (Basel, Switzerland) · 2020Article
- Random Forest Classification of Alcohol Use Disorder Using fMRI Functional Connectivity, Neuropsychological Functioning, and Impulsivity Measures.Brain sciences · 2020Article
- Neurofunctional Domains Derived From Deep Behavioral Phenotyping in Alcohol Use Disorder.The American journal of psychiatry · 2019Article
- A structural MRI study of differential neuromorphometric characteristics of binge and heavy drinking.Addictive behaviors reports · 2019Article
- A dual process perspective on advances in cognitive science and alcohol use disorder.Clinical psychology review · 2019Review
- Decreased event-related theta power and phase-synchrony in young binge drinkers during target detection: An anatomically-constrained MEG approach.Journal of psychopharmacology (Oxford, England) · 2019Article
- Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers.Brain connectivity · 2018Article
- The neural correlates of the unified percept of alcohol-related craving: a fMRI and EEG study.Scientific reports · 2018Article
- A Review of the Potential Mechanisms of Action of Baclofen in Alcohol Use Disorder.Frontiers in psychiatry · 2018Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlcohol causes damage to the brain and is associated with various functional impairments. However, much of the brain damage can be reversed by abstaining for enough time. This study aims to investigate the patterns and degrees of brain function in abstinent patients with alcohol dependence by using resting-state functional connectivity.
methods26 male patients with alcohol dependence (alcohol group) and 28 age-matched male healthy volunteers (control group) were recruited from a mental hospital and the community, respectively. Using 3T MRI scan data, the resting-state functional connectivity of the task-negative and task-positive networks was determined and compared between the groups.
resultsThere were no significant group differences in the resting-state functional connectivity in the default mode or in the salience and sensorimotor networks. Compared with the control group, the alcohol group showed significantly lower functional connectivity in the executive control network, especially in the cingulo-opercular network and, in some regions of interest, the dorsal attention network.
conclusionThis finding suggests that some brain networks do not normalize their functions after abstinence from drinking, and these results may be helpful in future research to investigate the mechanisms for craving alcohol and alcohol relapse prevention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.