Evidence map›Paper›PMID 28539927›Full record

ArticleFrontiers in plant science2017

A Comprehensive Analysis of Alternative Splicing in Paleopolyploid Maize.

Wenbin Mei, Sanzhen Liu, James C Schnable, Cheng-Ting Yeh, Nathan M Springer, Patrick S Schnable, William B Barbazuk

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 63 citations in OpenAlex.

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  16. Frontiers in plant science · 2020
    Article
  17. The Genetic Regulation of Alternative Splicing inFrontiers in plant science · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Wenbin MeiDepartment of Biology, University of Florida, GainesvilleFL, USA.
Sanzhen LiuDepartment of Agronomy, Iowa State University, AmesIA, USA.
James C SchnableDepartment of Agronomy and Horticulture, University of Nebraska-Lincoln, LincolnNE, USA.
Cheng-Ting YehDepartment of Agronomy, Iowa State University, AmesIA, USA.
Nathan M SpringerDepartment of Plant Biology, Microbial and Plant Genomics Institute, University of Minnesota, Saint PaulMN, USA.
Patrick S SchnableDepartment of Agronomy, Iowa State University, AmesIA, USA.
William B BarbazukDepartment of Biology, University of Florida, GainesvilleFL, USA.
Iowa State University · USUniversity of Florida · USKansas State University · USUniversity of Minnesota · USUniversity of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identifying and characterizing alternative splicing (AS) enables our understanding of the biological role of transcript isoform diversity. This study describes the use of publicly available RNA-Seq data to identify and characterize the global diversity of AS isoforms in maize using the inbred lines B73 and Mo17, and a related species, sorghum. Identification and characterization of AS within maize tissues revealed that genes expressed in seed exhibit the largest differential AS relative to other tissues examined. Additionally, differences in AS between the two genotypes B73 and Mo17 are greatest within genes expressed in seed. We demonstrate that changes in the level of alternatively spliced transcripts (intron retention and exon skipping) do not solely reflect differences in total transcript abundance, and we present evidence that intron retention may act to fine-tune gene expression across seed development stages. Furthermore, we have identified temperature sensitive AS in maize and demonstrate that drought-induced changes in AS involve distinct sets of genes in reproductive and vegetative tissues. Examining our identified AS isoforms within B73 × Mo17 recombinant inbred lines (RILs) identified splicing QTL (sQTL). The 43.3% of

Indexed as

abiotic stressalternative splicingmaizeseed developmentsorghumsplicing QTLwhole genome duplication

Identifiers

PMID28539927
PMCPMC5423905
OpenAlexW2613644388

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.