ArticleInternational journal of biological sciences2017
Recapitulating and Correcting Marfan Syndrome in a Cellular Model.
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Article in International journal of biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
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Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Structural Restoration of an Unruptured Vertebral Artery Dissection Following Autologous Mesenchymal Stem Cell Therapy: A Case Report.Clinical case reports · 2026Article
- Induced Pluripotent (iPSC) and Mesenchymal (MSC) Stem Cells for In Vitro Disease Modeling and Regenerative Medicine.International journal of molecular sciences · 2025Review
- Use of iPSC-Derived Smooth Muscle Cells to Model Physiology and Pathology.Arteriosclerosis, thrombosis, and vascular biology · 2024Review
- Human stem cell models for Marfan syndrome: aFrontiers in cell and developmental biology · 2024Review
- En route towards a personalized medicine approach: Innovative therapeutic modalities for connective tissue disorders.Matrix biology : journal of the International Society for Matrix Biology · 2023Review
- Stem Cell-Based Therapeutic Approaches in Genetic Diseases.Advances in experimental medicine and biology · 2023Article
- The extracellular matrix glycoprotein fibrillin-1 in health and disease.Frontiers in cell and developmental biology · 2023Review
- Creating an Optimal In Vivo Environment to Enhance Outcomes Using Cell Therapy to Repair/Regenerate Injured Tissues of the Musculoskeletal System.Biomedicines · 2022Review
- Genotype-phenotype correlations of marfan syndrome and related fibrillinopathies: Phenomenon and molecular relevance.Frontiers in genetics · 2022Review
- Effects of Simulated Microgravity on Wild Type and Marfan hiPSCs-Derived Embryoid Bodies.Cellular and molecular bioengineering · 2021Article
- Modeling aortic diseases using induced pluripotent stem cells.Stem cells translational medicine · 2021Review
- Effects of fibrillin mutations on the behavior of heart muscle cells in Marfan syndrome.Scientific reports · 2020Article
- Versatility of Induced Pluripotent Stem Cells (iPSCs) for Improving the Knowledge on Musculoskeletal Diseases.International journal of molecular sciences · 2020Review
- Identification of novel FBN1 variations implicated in congenital scoliosis.Journal of human genetics · 2020Article
- Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics.Pharmacological reviews · 2020Review
- Genetic and molecular mechanism for distinct clinical phenotypes conveyed by allelic truncating mutations implicated in FBN1.Molecular genetics & genomic medicine · 2020Article
- Genetic regulation of linear growth.Annals of pediatric endocrinology & metabolism · 2019Article
- The Application of Induced Pluripotent Stem Cells in Pathogenesis Study and Gene Therapy for Vascular Disorders: Current Progress and Future Challenges.Stem cells international · 2019Review
- Transplantation of human ESC-derived mesenchymal stem cell spheroids ameliorates spontaneous osteoarthritis in rhesus macaques.Theranostics · 2019Article
Corrections and comments
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Authors and funding
20 authors at 7 institutions in 3 countries.
Jung Woo ParkFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Li YanFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Chris StoddardDepartment of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.
Xiaofang WangDepartment of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.
Zhichao YueAgricultural Genomes Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Leann CrandallDepartment of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.
Tiwanna RobinsonDepartment of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.
Yuxiao ChangAgricultural Genomes Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Kyle DentonDepartment of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.
Enqin LiFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Bin JiangFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Zhenwu ZhangFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
Kristen Martins-TaylorDepartment of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.
Siu-Pok YeeDepartment of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.
Hong NieGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou, Guangdong, China.
Feng GuSchool of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, State Key Laboratory Cultivation Base and Key Laboratory of Vision Science, Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry, Wenzhou, Zhejiang, China.
Wei SiYunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, China.
Ting XieStowers Institute for Medical Research, Kansas City, Missouri, USA.
Lixia YueDepartment of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut, USA.
Ren-He XuFaculty of Health Sciences, University of Macau, Taipa, Macau, China.
UConn Health · USUniversity of Macau · MOAgricultural Genomics Institute at Shenzhen · CNAffiliated Eye Hospital of Wenzhou Medical College · CNJinan University · CNKunming University of Science and Technology · CNStowers Institute for Medical Research · US
Funding
Ca2+ signaling mechanisms in cardiac fibrosisR01HL078960 · NHLBI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI YUE, LIXIA · 2005 to 2015
$3.9MNHLBI NIH HHS R01 HL078960
Abstract
Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in
Indexed as
Cell DifferentiationCells, CulturedEmbryonic Stem CellsFibrillin-1Gene EditingHumansInduced Pluripotent Stem CellsMarfan SyndromeMicrofilament ProteinsMuscle, SmoothMutationOsteogenesisFibrillin-1Microfilament Proteinsdisease modelinggenome editinghuman pluripotent stem cellsMarfan syndromeosteogenesissmooth muscle.
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.