Evidence map›Paper›PMID 28539712›Full record

ArticlePharmacognosy magazine

Betulinic Acid from

Fernanda Carolina Sousa Fonseca, Letícia Caribé Batista Reis, Jener David Gonçalves Dos Santos, Carla Rodrigues Cardoso Branco, Sergio Luis da Costa Ferreira, Jorge Mauricio David, Alexsandro Branco

Abstract read
In one paragraph

Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fernanda Carolina Sousa FonsecaDepartment of Health, State University of Feira de Santana, Feira de Santana, Bahia, Brazil.
Letícia Caribé Batista ReisDepartment of Health, State University of Feira de Santana, Feira de Santana, Bahia, Brazil.
Jener David Gonçalves Dos SantosDepartment of Health, State University of Feira de Santana, Feira de Santana, Bahia, Brazil.
Carla Rodrigues Cardoso BrancoDepartment of Health, State University of Feira de Santana, Feira de Santana, Bahia, Brazil.
Sergio Luis da Costa FerreiraDepartment of Organic Chemistry, Federal University of Bahia, Salvador, Bahia, Brazil.
Jorge Mauricio DavidDepartment of Organic Chemistry, Federal University of Bahia, Salvador, Bahia, Brazil.
Alexsandro BrancoDepartment of Health, State University of Feira de Santana, Feira de Santana, Bahia, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of the extraction time (min) and temperature (°C) on the yield of betulinic acid (BA) from MATERIALS AND

methodsThe ethyl acetate was used as extractor solvent because it was shown to provide a betulinic acid-clean extract. A full two-level statistical factorial design was applied to determine the important effects and interactions of these independent variables upon the yield of BA.

resultsThe conditions that produced the highest yield of BA were at temperature of 70°C and an extraction time of 15 min (3.33 mg per gram of plant).

conclusionThe BA has drawn attention due to its use as a raw material in the synthesis of active compounds against the Human Immunodeficiency Virus (HIV). SUMMARY: The extraction of betulinic acid (BA) from

Indexed as

Betulinic acidexperimental designfocused microwave assisted extractionZizyphus joazeiro

Identifiers

PMID28539712
PMCPMC5421417

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.