Evidence map›Paper›PMID 28539707›Full record

ReviewMediators of inflammation2017

Effector and Regulatory T Cell Trafficking in Corneal Allograft Rejection.

Afsaneh Amouzegar, Sunil K Chauhan

Open access · goldAbstract readReview
In one paragraph

Review in Mediators of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. The impact of donor diabetes on corneal transplant immunity.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  8. Article
  9. Article
  10. Corneal Allografts: Factors for and against Acceptance.Journal of immunology research · 2021
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Afsaneh AmouzegarSchepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.ORCID 0000-0001-5831-1387
Sunil K ChauhanSchepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.ORCID 0000-0003-4938-6023
Massachusetts Eye and Ear Infirmary · US

Funding

Ocular Immune Regulation by Mesenchymal Stem CellsR01EY024602 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI CHAUHAN, SUNIL K · 2015 to 2025
$6.5M
NEI NIH HHS R01 EY024602
6 · The paper itself

Abstract

Corneal transplantation is among the most prevalent and successful forms of solid tissue transplantation in humans. Failure of corneal allograft is mainly due to immune-mediated destruction of the graft, a complex and highly coordinated process that involves elaborate interactions between cells of innate and adaptive immunity. The migration of immune cells to regional lymphoid tissues and to the site of graft plays a central role in the immunopathogenesis of graft rejection. Intricate interactions between adhesion molecules and their counter receptors on immune cells in conjunction with tissue-specific chemokines guide the trafficking of these cells to the draining lymph nodes and ultimately to the site of graft. In this review, we discuss the cascade of chemokines and adhesion molecules that mediate the trafficking of effector and regulatory T cells during corneal allograft rejection.

Indexed as

Adaptive ImmunityAllograftsAnimalsCorneal TransplantationGraft RejectionHumansImmunity, InnateT-Lymphocytes, Regulatory

Identifiers

PMID28539707
PMCPMC5429952
OpenAlexW2608212979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.