Evidence map›Paper›PMID 28539654›Full record

ArticleScientific reports2017

Quasispecies composition and evolution of a typical Zika virus clinical isolate from Suriname.

Sander van Boheemen, Ali Tas, S Yahya Anvar, Rebecca van Grootveld, Irina C Albulescu, Martijn P Bauer, Mariet C Feltkamp, Peter J Bredenbeek, Martijn J van Hemert

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Evolution of Zika virus inVirus evolution · 2025
    Article
  3. Article
  4. African ZIKV lineage fails to sustain infectivity in an in vitro mimetic urban cycle.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Zika Virus Potential Vectors amongPathogens (Basel, Switzerland) · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Viral quasispecies.PLoS genetics · 2019
    Article
  14. Impact of RNA Virus Evolution on Quasispecies Formation and Virulence.International journal of molecular sciences · 2019
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sander van BoheemenDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
Ali TasDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
S Yahya AnvarDepartment of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Rebecca van GrootveldDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
Irina C AlbulescuDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
Martijn P BauerDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Mariet C FeltkampDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-5993-9846
Peter J BredenbeekDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
Martijn J van HemertDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands. M.J.van_Hemert@lumc.nl.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The arthropod-borne Zika virus (ZIKV) is currently causing a major international public health threat in the Americas. This study describes the isolation of ZIKV from the plasma of a 29-year-old female traveler that developed typical symptoms, like rash, fever and headache upon return from Suriname. The complete genome sequence including the 5' and 3' untranslated regions was determined and phylogenetic analysis showed the isolate clustering within the Asian lineage, close to other viruses that have recently been isolated in the Americas. In addition, the viral quasispecies composition was analyzed by single molecule real time sequencing, which suggested a mutation frequency of 1.4 × 10

Indexed as

QuasispeciesAdultAmericasAnimalsChlorocebus aethiopsFemaleGenome, ViralHumansPhylogenySurinameTravelVero CellsViral Envelope ProteinsViral Nonstructural ProteinsZika VirusZika Virus InfectionViral Envelope ProteinsViral Nonstructural Proteins

Identifiers

PMID28539654
PMCPMC5443807
OpenAlexW2614677038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.