Evidence map›Paper›PMID 28539480›Full record

ArticleJournal of the Royal Society, Interface2017

Identification of vortex structures in a cohort of 204 intracranial aneurysms.

Nicole Varble, Gabriel Trylesinski, Jianping Xiang, Kenneth Snyder, Hui Meng

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. What does computational fluid dynamics tell us about intracranial aneurysms? A meta-analysis and critical review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicole VarbleDepartment of Mechanical and Aerospace Engineering, University at Buffalo, State University of New York, Buffalo, NY, USA.ORCID 0000-0003-2273-7962
Gabriel TrylesinskiDepartment of Mechanical and Aerospace Engineering, University at Buffalo, State University of New York, Buffalo, NY, USA.
Jianping XiangToshiba Stroke and Vascular Research Center, University at Buffalo, State University of New York, Buffalo, NY, USA.
Kenneth SnyderToshiba Stroke and Vascular Research Center, University at Buffalo, State University of New York, Buffalo, NY, USA.
Hui MengDepartment of Mechanical and Aerospace Engineering, University at Buffalo, State University of New York, Buffalo, NY, USA huimeng@buffalo.edu.
Toshiba (United States) · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Virtual Intervention of Intracranial AneurysmsR01NS091075 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MENG, HUI · 2015 to 2019
$1.7M
AView: A Bedside Simulation Tool for Neurovascular InterventionR03NS090193 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MENG, HUI · 2015 to 2016
$157k
NCATS NIH HHS UL1 TR001412NINDS NIH HHS R01 NS091075NINDS NIH HHS R03 NS090193
6 · The paper itself

Abstract

An intracranial aneurysm (IA) is a cerebrovascular pathology that can lead to death or disability if ruptured. Abnormal wall shear stress (WSS) has been associated with IA growth and rupture, but little is known about the underlying flow physics related to rupture-prone IAs. Previous studies, based on analysis of a few aneurysms or partial views of three-dimensional vortex structures, suggest that rupture is associated with complex vortical flow inside IAs. To further elucidate the relevance of vortical flow in aneurysm pathophysiology, we studied 204 patient IAs (56 ruptured and 148 unruptured). Using objective quantities to identify three-dimensional vortex structures, we investigated the characteristics associated with aneurysm rupture and if these features correlate with previously proposed WSS and morphological characteristics indicative of IA rupture. Based on the

Indexed as

Cerebrovascular CirculationComputer SimulationHydrodynamicsModels, CardiovascularAneurysm, RupturedBiomechanical PhenomenaCohort StudiesHemodynamicsHumansImaging, Three-DimensionalIntracranial Aneurysmimage-based computational fluid dynamicsintracranial aneurysmsrupturevortex structures

Identifiers

PMID28539480
PMCPMC5454289
OpenAlexW2617632502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.