Evidence map›Paper›PMID 28539478›Full record

ArticleEMBO molecular medicine2017

A novel epigenetic

Yonghui Li, Qiaoyang Ning, Jinlong Shi, Yang Chen, Mengmeng Jiang, Li Gao, Wenrong Huang, Yu Jing, Sai Huang, Anqi Liu and 7 more

Abstract read
In one paragraph

Article in EMBO molecular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Hypomethylation ofFrontiers in immunology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. [Characteristics of N6-methyladenosine modification patterns in t(8;21) acute myeloid leukemia].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Inhibition of miR-383 suppresses oxidative stress and improves endothelial function by increasing sirtuin 1.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020
    Article
  15. Review
  16. A novel epigeneticEMBO molecular medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yonghui LiDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0001-6782-7473
Qiaoyang NingDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.
Jinlong ShiDepartment of Biomedical Engineering, Chinese PLA General Hospital, Beijing, China.
Yang ChenKey Laboratory of Bioinformatics, Tsinghua University, Beijing, China.
Mengmeng JiangDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.
Li GaoDepartment of Haematology, China-Japan Friendship Hospital, Beijing, China.
Wenrong HuangDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.
Yu JingDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.
Sai HuangDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.
Anqi LiuDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.
Zhirui HuKey Laboratory of Bioinformatics, Tsinghua University, Beijing, China.
Daihong LiuDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.
Lili WangDepartment of Haematology, Chinese PLA General Hospital, Beijing, China.
Clara NerviDepartment of Medico-Surgical Sciences and Biotechnologies, University of Rome "La Sapienza" Polo Pontino, Latina, Italy.
Yun DaiCancer Centre, The First Hospital of Jilin University, Changchun, China.
Michael Q ZhangKey Laboratory of Bioinformatics, Tsinghua University, Beijing, China.
Li YuDepartment of Haematology, Chinese PLA General Hospital, Beijing, China liyu301@vip.163.com.ORCID 0000-0001-6872-2665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation patterns are frequently deregulated in t(8;21) acute myeloid leukaemia (AML), but little is known of the mechanisms by which specific gene sets become aberrantly methylated. Here, we found that the promoter DNA methylation signature of t(8;21)

Indexed as

CarcinogenesisEpigenesis, GeneticAnimalsCell Line, TumorCore Binding Factor Alpha 2 SubunitDisease Models, AnimalDNA-Binding ProteinsDNA MethylationDown-RegulationFemaleHeterograftsHumansLeukemia, Myeloid, AcuteMice, Inbred BALB CMicroRNAsPromoter Regions, GeneticCore Binding Factor Alpha 2 SubunitDNA-Binding ProteinsMicroRNAsMIRN383 microRNA, humanRUNX1 protein, humanRUNX1T1 protein, humanRUNX1 Translocation Partner 1 ProteinTHAP10 protein, humanAML1‐ETOepigeneticsmiR‐383t(8;21) AMLTHAP10

Identifiers

PMID28539478
PMCPMC5577530

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.