Evidence map›Paper›PMID 28539386›Full record

ArticleThe Journal of cell biology2017

DNA replication timing influences gene expression level.

Carolin A Müller, Conrad A Nieduszynski

Abstract readComparative Study
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The evolution of the human DNA replication timing program.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
  9. Article
  10. Genes · 2022
    Review
  11. Diversity of Giant Viruses InfectingFrontiers in microbiology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Mammalian DNA Replication Timing.Cold Spring Harbor perspectives in biology · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Sir2 mitigates an intrinsic imbalance in origin licensing efficiency between early- and late-replicating euchromatin.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carolin A MüllerSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.ORCID 0000-0002-7422-5582
Conrad A NieduszynskiSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK conrad.nieduszynski@path.ox.ac.uk.ORCID 0000-0003-2001-076X

Funding

Biotechnology and Biological Sciences Research Council BB/K007211/1Biotechnology and Biological Sciences Research Council BB/K007211/2Biotechnology and Biological Sciences Research Council BB/N016858/1
6 · The paper itself

Abstract

Eukaryotic genomes are replicated in a reproducible temporal order; however, the physiological significance is poorly understood. We compared replication timing in divergent yeast species and identified genomic features with conserved replication times. Histone genes were among the earliest replicating loci in all species. We specifically delayed the replication of

Indexed as

DNA Replication TimingGene Expression Regulation, FungalCell Cycle ProteinsDNA, FungalHistone AcetyltransferasesHistonesMutationPhylogenyRNA, FungalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTime FactorsTranscription, GeneticCell Cycle ProteinsDNA, FungalHistone AcetyltransferasesHistonesRNA, FungalRtt109 protein, S cerevisiaeSaccharomyces cerevisiae Proteins

Identifiers

PMID28539386
PMCPMC5496624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.