Trial reportJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
Effects that passive cycling exercise have on muscle strength, duration of mechanical ventilation, and length of hospital stay in critically ill patients: a randomized clinical trial.
Trial report in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of Early Mobilization Protocol in Patients in the ICU of the University Hospital of Santa Maria.
Effects of Exercise Intervention on Muscle Strength in Severely Ill Patients
Who cites it
31 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Korean clinical practice guidelines for rehabilitation in critically ill patients and post-intensive care syndrome.Acute and critical care · 2026Guideline
- Effects of Cycle Ergometer Exercise on Functional Capacity and Hospitalization Time of Patients After Open-Heart Surgery: A Systematic Review and Meta-Analysis.Brazilian journal of cardiovascular surgery · 2026Pooled it
- In-bed cycling for adult intensive care patients: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Systematic review and meta-analysis of physical rehabilitation on functional recovery in critically ill patients.Frontiers in medicine · 2026Pooled it
- Effectiveness of Nurse-Led Early Mobility Protocols on the Outcomes of Critical Care Patients: A Systematic Review and Meta-Analysis.Nursing open · 2025Pooled it
- Reporting of nutritional screening, status, and intake in trials of nutritional and physical rehabilitation following critical illness: a systematic review.The American journal of clinical nutrition · 2025Pooled it
- Guideline on positioning and early mobilisation in the critically ill by an expert panel.Intensive care medicine · 2024Guideline
- Pooled it
- Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Indirect calorimetry directed feeding and cycling in the older ICU population: a pilot randomised controlled trial.BMC anesthesiology · 2024Trial
- Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients.BMJ open respiratory research · 2019Trial
- Korean Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients and Post-Intensive Care Syndrome.Annals of rehabilitation medicine · 2026Article
- Nurse-Led Early Mobility Protocols in the Intensive Care Unit.Nursing open · 2025Article
- Early Neuromuscular Electrical Stimulation and In-Bed Leg Cycling Preserve Quadriceps Femoris Muscle Thickness in Critically Ill Patients.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025Article
- Respiratory Muscle Training in Mechanically Ventilated Adult Patients: Toward a Precise Prescription Based on Current Evidence: A Scoping Review.Journal of clinical medicine · 2025Review
- Myokine Secretion Dynamics and Their Role in Critically Ill Patients: A Scoping Review.Journal of clinical medicine · 2025Review
- Current Concepts in Early Mobilization of Critically Ill Patients Within the Context of Neurologic Pathology.Neurocritical care · 2024Review
- Early Rehabilitation Activity and Rehabilitation in ICU Wards in Central China: A Cross-Sectional Survey.Risk management and healthcare policy · 2024Article
- Japanese Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients 2023 (J-ReCIP 2023).Journal of intensive care · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the effects that passive cycling exercise, in combination with conventional physical therapy, have on peripheral muscle strength, duration of mechanical ventilation, and length of hospital stay in critically ill patients admitted to the ICU of a tertiary care university hospital. Methods: This was a randomized clinical trial involving 38 patients (≥ 18 years of age) on mechanical ventilation who were randomly divided into two groups: control (n = 16), receiving conventional physical therapy; and intervention (n = 22), receiving conventional physical therapy and engaging in passive cycling exercise five days per week. The mean age of the patients was 46.42 ± 16.25 years, and 23 were male. The outcomes studied were peripheral muscle strength, as measured by the Medical Research Council scale, duration of mechanical ventilation, and length of hospital stay. Results: There was a significant increase in peripheral muscle strength (baseline vs. final) in both groups (control: 40.81 ± 7.68 vs. 45.00 ± 6.89; and intervention: 38.73 ± 11.11 vs. 47.18 ± 8.75; p < 0.001 for both). However, the range of increase in strength was higher in the intervention group than in the control group (8.45 ± 5.20 vs. 4.18 ± 2.63; p = 0.005). There were no significant differences between the groups in terms of duration of mechanical ventilation or length of hospital stay. Conclusions: The results suggest that the performance of continuous passive mobilization on a cyclical basis helps to recover peripheral muscle strength in ICU patients. (ClinicalTrials.gov Identifier: NCT01769846 [http://www.clinicaltrials.gov/]).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.