Evidence map›Paper›PMID 28538706›Full record

ReviewInternational journal of molecular sciences2017

The Importance of Pericytes in Healing: Wounds and other Pathologies.

Hannah Thomas, Allison J Cowin, Stuart J Mills

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 74 citations in OpenAlex.

  1. Trial
  2. Review
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  4. Article
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  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Evidence for the in vivo existence and mobilisation of myeloid angiogenic cells and pericyte-like cells in wound patients after skin grafting.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2023
    Article
  13. Long-termAdipocyte · 2022
    Article
  14. Ninjurin1 Deletion in NG2-Positive Pericytes Prevents Microvessel Maturation and Delays Wound Healing.JID innovations : skin science from molecules to population health · 2022
    Article
  15. Review
  16. Fibroblast Heterogeneity in Healthy and Wounded Skin.Cold Spring Harbor perspectives in biology · 2022
    Article
  17. Review
  18. Review
  19. Therapeutic Effect of Pericytes for Diabetic Wound Healing.Frontiers in cardiovascular medicine · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hannah ThomasCentre for Regenerative Medicine, Future Industries Institute, University of South Australia, Mawson Lakes 5095, Australia. hannah.thomas@mymail.unisa.edu.au.
Allison J CowinCentre for Regenerative Medicine, Future Industries Institute, University of South Australia, Mawson Lakes 5095, Australia. allison.cowin@unisa.edu.au.
Stuart J MillsCentre for Regenerative Medicine, Future Industries Institute, University of South Australia, Mawson Lakes 5095, Australia. stuart.mills@unisa.edu.au.
University of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Much of current research investigates the beneficial properties of mesenchymal stem cells (MSCs) as a treatment for wounds and other forms of injury. In this review, we bring attention to and discuss the role of the pericyte, a cell type which shares much of the differentiation potential and regenerative properties of the MSC as well as specific roles in the regulation of angiogenesis, inflammation and fibrosis. Pericytes have been identified as dysfunctional or depleted in many disease states, and observing the outcomes of pericyte perturbation in models of disease and wound healing informs our understanding of overall pericyte function and identifies these cells as an important target in the development of therapies to encourage healing.

Indexed as

Wound HealingAnimalsHumansInflammationMesenchymal Stem CellsMesenchymal Stem Cell TransplantationNeovascularization, PhysiologicPericytescell therapyMSCpericytewound healing

Identifiers

PMID28538706
PMCPMC5485953
OpenAlexW2618007314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.