ReviewNeonatology2017
Surfactant for Respiratory Distress Syndrome: New Ideas on a Familiar Drug with Innovative Applications.
Review in Neonatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03989960 (Application of Modified Intubation-surfactant-extubation), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application of Modified Intubation-surfactant-extubation (InSurE) Technique in Preterm Neonates With Respiratory Distress Syndrome
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Pooled it
- Surfactant-Enabled Nanocarriers in Breast Cancer Therapy: Targeted Delivery and Multidrug Resistance Reversal.Pharmaceutics · 2025Review
- Article
- RDS-NExT workshop: consensus statements for the use of surfactant in preterm neonates with RDS.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Artificial Intelligence-Driven Respiratory Distress Syndrome Prediction for Very Low Birth Weight Infants: Korean Multicenter Prospective Cohort Study.Journal of medical Internet research · 2023Article
- A recipe for a good clinical pulmonary surfactant.Biomedical journal · 2022Review
- New perpective for an old problem: extracellular vesicle based management of respiratory distress syndrome.Drug delivery · 2021Article
- Association of Adherence to Surfactant Best Practice Uses With Clinical Outcomes Among Neonates in Sweden.JAMA network open · 2021Observational
- Weight Is More Accurate than Gestational Age When Estimating the Optimal Endotracheal Tube Depth in Neonates.Children (Basel, Switzerland) · 2021Article
- Guidelines for surfactant replacement therapy in neonates.Paediatrics & child health · 2021Review
- Does surfactant nebulization prevent early intubation in preterm infants? A protocol for a systematic review and meta-analysis.Systematic reviews · 2021Article
- Nutritional approach for increasing public health during pandemic of COVID-19: A comprehensive review of antiviral nutrients and nutraceuticals.Health promotion perspectives · 2021Review
- The Effect of Exogenous Surfactant on Moderate and Severe Stages of COVID-19 Induced ARDS: the Pilot Study of a Clinical Trial.Iranian journal of pharmaceutical research : IJPR · 2021Article
- [Risk factors for minimally invasive surfactant administration failure in preterm infants with respiratory distress syndrome].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- From bench to bedside: in vitro and in vivo evaluation of a neonate-focused nebulized surfactant delivery strategy.Respiratory research · 2019Article
- History of Pulmonary Surfactant Replacement Therapy for Neonatal Respiratory Distress Syndrome in Korea.Journal of Korean medical science · 2019Review
- Can laryngeal mask airway be used for surfactant administration in neonates?Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- Neonatal Respiratory Distress Syndrome: Tackling A Worldwide Problem.P & T : a peer-reviewed journal for formulary management · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last 4 decades, advances in neonatology have led to a significant increase in the survival of preterm infants. One of the biggest advances was the introduction of surfactant replacement therapy for the treatment of respiratory distress syndrome. This is the main cause of respiratory insufficiency in preterm infants and is one of the major causes of perinatal morbidity and mortality. Surfactant replacement therapy is already a well-investigated and established therapy in neonatology. However, surfactant replacement therapy has progressed and been refined over recent decades, especially with the increasing care for preterm infants born before 26 weeks' gestational age and the recent clinical focus on avoiding mechanical ventilation. Clinical evidence is evolving on new types of surfactant, surfactant dosages, co-medication given before, with, or after surfactant replacement, and new technical advances regarding the mode of administration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.