Evidence map›Paper›PMID 28538155›Full record

ArticleBiophysical journal2017

Structure and Intermolecular Interactions between L-Type Straight Flagellar Filaments.

Daniel Louzon, Avi Ginsburg, Walter Schwenger, Tom Dvir, Zvonimir Dogic, Uri Raviv

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Sound-mediated nucleation and growth of amyloid fibrils.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  2. Upgrade ofJournal of applied crystallography · 2023
    Article
  3. Bonded straight and helical flagellar filaments form ultra-low-density glasses.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Modulating amyloids' formation path with sound energy.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Article
  6. Journal of applied crystallography · 2019
    Article
  7. Article
  8. Interacting Bacteria Surfaces.Biophysical journal · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Daniel LouzonThe Institute of Chemistry and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, Israel; The Racah Institute of Physics, The Hebrew University of Jerusalem, Jerusalem, Israel.
Avi GinsburgThe Institute of Chemistry and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, Israel; The Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.
Walter SchwengerDepartment of Physics, Brandeis University, Waltham, Massachusetts.
Tom DvirThe Institute of Chemistry and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, Israel; The Racah Institute of Physics, The Hebrew University of Jerusalem, Jerusalem, Israel.
Zvonimir DogicDepartment of Physics, Brandeis University, Waltham, Massachusetts.
Uri RavivThe Institute of Chemistry and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address: uri.raviv@mail.huji.ac.il.
Hebrew University of Jerusalem · ILBrandeis University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial mobility is powered by rotation of helical flagellar filaments driven by rotary motors. Flagellin isolated from the Salmonella Typhimurium SJW1660 strain, which differs by a point mutation from the wild-type strain, assembles into straight filaments in which flagellin monomers are arranged in a left-handed helix. Using small-angle x-ray scattering and osmotic stress methods, we investigated the structure of SJW1660 flagellar filaments as well as the intermolecular forces that govern their assembly into dense hexagonal bundles. The scattering data were fitted to models, which took into account the atomic structure of the flagellin subunits. The analysis revealed the exact helical arrangement and the super-helical twist of the flagellin subunits within the filaments. Under osmotic stress, the filaments formed two-dimensional hexagonal bundles. Monte Carlo simulations and continuum theories were used to analyze the scattering data from hexagonal arrays, revealing how the bundle bulk modulus and the deflection length of filaments in the bundles depend on the applied osmotic stress. Scattering data from aligned flagellar bundles confirmed the theoretically predicated structure-factor scattering peak line shape. Quantitative analysis of the measured equation of state of the bundles revealed the contributions of electrostatic, hydration, and elastic interactions to the intermolecular forces associated with bundling of straight semi-flexible flagellar filaments.

Indexed as

Computer SimulationElasticityFlagellaFlagellinModels, MolecularMonte Carlo MethodOsmotic PressurePressureSalmonella typhimuriumScattering, Small AngleX-Ray DiffractionFlagellin

Identifiers

PMID28538155
PMCPMC5443976
OpenAlexW2617612657

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.