Evidence map›Paper›PMID 28538003›Full record

ReviewCurrent opinion in obstetrics & gynecology2017

Use of fertility medications and cancer risk: a review and update.

Lindsay Kroener, Daniel Dumesic, Zain Al-Safi

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in obstetrics & gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
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  7. Article
  8. Review
  9. Article
  10. Review
  11. Hormone therapy and melanoma in women.International journal of women's dermatology · 2021
    Review
  12. Review
  13. Article
  14. Exploring Reproductive Health Education Needs in Infertile Women in Iran: A Qualitative Study.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2020
    Article
  15. Article
  16. Review
  17. Ddx4Cells · 2019
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lindsay KroenerDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Daniel Dumesic
Zain Al-Safi
University of California, Los Angeles · US

Funding

PROJECT 4: ANDROGEN EXCESS IN ADIPOGENIC DYSFUNCTION IN PCOS WOMENP50HD071836 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI STOUFFER, RICHARD L · 2014 to 2021
$14.7M
NICHD NIH HHS P50 HD071836
6 · The paper itself

Abstract

purpose of reviewThere is increasing use of fertility medications for ovulation induction and ovarian stimulation for in-vitro fertilization in the treatment of female infertility. In this review, recent literature regarding the association between fertility medication and cancer risk is reviewed. RECENT

findingsSeveral important publications have recently addressed the relationship between use of fertility medications and cancer risk. There are methodological limitations to many of these studies, including unique challenges in studying rare cancers that often develop several years after the time of fertility medication exposure. Although infertility per se is a risk factor for some female cancers, including breast, endometrial and ovarian cancer, most studies do not show a significant risk of these cancers with the use of fertility medications. Some studies, however, have shown a possible increased relative risk of borderline ovarian cancer, although the increased absolute risk is small without a clear causal relationship. SUMMARY: The collective data regarding the risk of developing cancer from use of fertility medications are reassuring, although several methodological issues in these studies limit definitive conclusions.

Indexed as

Breast NeoplasmsColorectal NeoplasmsFemaleFertilityFertility Agents, FemaleFertilization in VitroHumansInfertility, FemaleMelanomaNeoplasmsOvarian NeoplasmsOvulation InductionPrognosisRisk FactorsThyroid NeoplasmsUterine Cervical NeoplasmsFertility Agents, Female

Identifiers

PMID28538003
PMCPMC5551049
OpenAlexW2619614907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.