Evidence map›Paper›PMID 28537849›Full record

Trial reportNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2017

Efficacy, Safety, and Preparation of Standardized Parenteral Nutrition Regimens: Three-Chamber Bags vs Compounded Monobags-A Prospective, Multicenter, Randomized, Single-Blind Clinical Trial.

Jianchun Yu, Guohao Wu, Yun Tang, Yingjiang Ye, Zhongtao Zhang

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Quality improvement for parenteral nutrition in hospital: Applying a gap analysis to an electronic health record to review parenteral nutrition processing.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Review
  4. [Numerical study on the effect of the geometry size of multi-chamber infusion bag on its bursting force].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
    Article
  5. [Finite element method simulating bursting process of multi-chamber flexible package infusion bag].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jianchun Yu1 Department of General Surgery, Peking Union Medical College Hospital, CAMS&PUMC, Beijing, China.
Guohao Wu2 Department of General Surgery, Zhongshan Hospital Fudan University, Shanghai, China.
Yun Tang3 Department of General Surgery, The PLA General Hospital of China, Beijing, China.
Yingjiang Ye4 Department of General Surgery, Peking University People's Hospital, Beijing, China.
Zhongtao Zhang5 Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParenteral nutrition (PN) covering the need for carbohydrates, amino acids, and lipids can either be compounded from single nutrients or purchased as an industrially manufactured ready-to-use regimen. This study compares a commercially available 3-chamber bag (study group) with a conventionally compounded monobag regarding nutrition efficacy, safety, and regimen preparation time. MATERIALS AND

methodsThis prospective, randomized, single-blind study was conducted at 5 Chinese hospitals from October 2010-October 2011. Postsurgical patients requiring PN for at least 6 days were randomly assigned to receive the study or control regimen. Plasma concentrations of prealbumin and C-reactive protein (CRP), regimen preparation time, length of hospital stay (LOS), 30-day mortality, safety laboratory parameters, and adverse events (AEs) were recorded.

resultsIn total, 240 patients (121 vs 119 in study and control groups) participated in this study. Changes in prealbumin concentrations during nutrition support (Δ

conclusionThe PN regimen provided by the 3-chamber bag was comparable to the compounded regimen and safe in use. Time savings during regimen preparation indicates that use of 3-chamber bags simplifies the process of regimen preparation.

Indexed as

Drug CompoundingParenteral NutritionAdolescentAdultAgedAged, 80 and overBody Mass IndexC-Reactive ProteinFemaleFollow-Up StudiesHumansLength of StayMaleMiddle AgedParenteral Nutrition SolutionsPatient ComplianceC-Reactive ProteinParenteral Nutrition SolutionsPrealbumin3-chamber bagscompoundingefficacymultichamber bagsnutritional supportparenteral nutritionparenteral nutrition solutionspatienttreatment outcome

Identifiers

PMID28537849
PMCPMC5542131

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.