Evidence map›Paper›PMID 28537595›Full record

ArticleNature chemistry2017

Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization.

Jia Niu, David J Lunn, Anusha Pusuluri, Justin I Yoo, Michelle A O'Malley, Samir Mitragotri, H Tom Soh, Craig J Hawker

Abstract read
PubMed Publisher
In one paragraph

Article in Nature chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed.

  1. Review
  2. Radical Polymerization in Living Systems.Polymer science & technology (Washington, D.C.) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Polymerization from Lipid Membranes.Biomacromolecules · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Catalyzing PET-RAFT Polymerizations Using Inherently Photoactive Zinc Myoglobin.Angewandte Chemie (International ed. in English) · 2025
    Article
  18. Article
  19. Article
  20. Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jia NiuCalifornia NanoSystems Institute, University of California, Santa Barbara, California 93106, USA.ORCID 0000-0002-5622-6362
David J LunnMaterials Research Laboratory, University of California, Santa Barbara, California 93106, USA.
Anusha PusuluriDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, USA.
Justin I YooDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, USA.
Michelle A O'MalleyDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, USA.
Samir MitragotriDepartment of Chemical Engineering, University of California, Santa Barbara, California 93106, USA.
H Tom SohDepartment of Radiology, School of Medicine, Stanford University, Stanford, California 94305, USA.
Craig J HawkerCalifornia NanoSystems Institute, University of California, Santa Barbara, California 93106, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The capability to graft synthetic polymers onto the surfaces of live cells offers the potential to manipulate and control their phenotype and underlying cellular processes. Conventional grafting-to strategies for conjugating preformed polymers to cell surfaces are limited by low polymer grafting efficiency. Here we report an alternative grafting-from strategy for directly engineering the surfaces of live yeast and mammalian cells through cell surface-initiated controlled radical polymerization. By developing cytocompatible PET-RAFT (photoinduced electron transfer-reversible addition-fragmentation chain-transfer polymerization), synthetic polymers with narrow polydispersity (M

Indexed as

Cell EngineeringPolymerizationCell CommunicationCells, CulturedCell SurvivalFree RadicalsHumansJurkat CellsPolymersSaccharomyces cerevisiaeSurface PropertiesFree RadicalsPolymers

Identifiers

PMID28537595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.