Evidence map›Paper›PMID 28537546›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

Biological characterisation of the emerged highly pathogenic avian influenza (HPAI) A(H7N9) viruses in humans, in mainland China, 2016 to 2017.

Wenfei Zhu, Jianfang Zhou, Zi Li, Lei Yang, Xiyan Li, Weijuan Huang, Sumei Zou, Wenbing Chen, Hejiang Wei, Jing Tang and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

  1. Pooled it
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  17. H7N9 Influenza Virus in China.Cold Spring Harbor perspectives in medicine · 2021
    Review
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  20. Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Wenfei ZhuNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Jianfang ZhouNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Zi LiNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Lei YangNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Xiyan LiNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Weijuan HuangNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Sumei ZouNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Wenbing ChenNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Hejiang WeiNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Jing TangNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Liqi LiuNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Jie DongNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Dayan WangNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
Yuelong ShuNational Institute for Viral Disease Control and Prevention, China Centers for Disease Control and Prevention, Key Laboratory for Medical Virology, National Health and Family Planning Commission, Beijing, China.
National Health and Family Planning Commission · CNNational Institute for Viral Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With no or low virulence in poultry, avian influenza A(H7N9) virus has caused severe infections in humans. In the current fifth epidemic wave, a highly pathogenic avian influenza (HPAI) H7N9 virus emerged. The insertion of four amino acids (KRTA) at the haemagglutinin (HA) cleavage site enabled trypsin-independent infectivity of this virus. Although maintaining dual receptor-binding preference, its HA antigenicity was distinct from low-pathogenic avian influenza A(H7N9). The neuraminidase substitution R292K conferred a multidrug resistance phenotype.

Indexed as

Disease OutbreaksAnimalsAntiviral AgentsChinaFemaleHemagglutinin Glycoproteins, Influenza VirusHumansInfluenza A Virus, H7N9 SubtypeInfluenza, HumanInfluenza in BirdsNeuraminidasePoultryViral LoadVirulenceAntiviral AgentsHemagglutinin Glycoproteins, Influenza VirusNeuraminidaseAntigenic analysisDrug sensitivityHighly pathogenic H7N9 virusesHPAIReceptor binding profile

Identifiers

PMID28537546
PMCPMC5476987
OpenAlexW2618395049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.