Evidence map›Paper›PMID 28537521›Full record

ArticleSeminars in ophthalmology2018

The Water-Drinking Test Revisited: An Analysis of Test Results in Subjects with Glaucoma.

M Reza Razeghinejad, Zahra Tajbakhsh, M Hossein Nowroozzadeh, Shane J Havens, Deepta Ghate, Vikas Gulati

Abstract read
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In one paragraph

Article in Seminars in ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

M Reza Razeghinejada Poostchi Eye Research Center , Shiraz University of Medical Sciences , Shiraz , Iran.ORCID http://orcid.org/0000-0001-7961-8425
Zahra Tajbakhsha Poostchi Eye Research Center , Shiraz University of Medical Sciences , Shiraz , Iran.
M Hossein Nowroozzadeha Poostchi Eye Research Center , Shiraz University of Medical Sciences , Shiraz , Iran.
Shane J Havensb Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA.
Deepta Ghateb Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA.
Vikas Gulatib Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA.
Shiraz University of Medical Sciences · IRUniversity of Nebraska Medical Center · US

Funding

Study of Aqueous Humor Dynamics in a Pediatric PopulationK23EY023266 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GULATI, VIKAS · 2013 to 2017
$1.1M
NEI NIH HHS K23 EY023266
6 · The paper itself

Abstract

purposeThe Water-Drinking Test (WDT) has been shown to predict the diurnal IOP change. This study evaluates the factors that may affect the WDT results.

methodsThis study was conducted on 203 glaucoma patients who had undergone trabeculectomy (53) or tube surgery (31), or had a medically controlled open-angle (82) or closed-angle (37) glaucoma. IOP was measured at baseline and then every 15 minutes over a one-hour period after drinking water. The main outcome measures were IOP change (increase in IOP from baseline) at all measurement time points, IOP peak (highest IOP after drinking water), IOP fluctuation (difference between IOP peak and baseline), and assessing the association of these IOPs with a patient's demographic and management modalities.

resultsThe mean age of the participants was 54±18 years, and 113 (56%) were male. Female patients showed greater IOP fluctuation than males (7.28 vs. 5.92 mm Hg; P=0.016), and a greater IOP peak (22.7 vs. 20.1 mm Hg; P=0.001). The observed associations between gender and IOP changes were only significant in <50 years. IOP at 60 minutes was greater in tube than trabeculectomy (5.6 vs. 3.1 mm Hg; P=0.007). The number of topical medications showed a direct independent association with IOP changes (P<0.001). Compared to other classes of topical medications, latanoprost showed lower WDT-IOP profile (P=0.0003).

conclusionsWDT-IOP change was diminished in subjects on latanoprost, and was greater in females <50 years, and those on greater number of medications.

Indexed as

Diagnostic Techniques, OphthalmologicalDrinkingAdolescentAdultAgedAged, 80 and overChildFemaleGlaucomaHumansIntraocular PressureMaleMiddle AgedPrognosisTrabeculectomyWaterWaterGlaucomatrabeculectomytube surgerywater-drinking test

Identifiers

PMID28537521
PMCPMC5701879
OpenAlexW2618362183

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.