ArticleAmerican journal of respiratory and critical care medicine2017
Core Outcome Measures for Clinical Research in Acute Respiratory Failure Survivors. An International Modified Delphi Consensus Study.
Article in American journal of respiratory and critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 231 papers, 18 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of High Versus Standard Enteral Protein Provision on Functional Recovery Following Intensive Care Admission: a Randomized Controlled, Multicenter, Parallel Group Trial in Mechanically Ventilated, Critically Ill Patients
Pneumococcal Community-Acquired Pneumonia Requiring Hospitalization Among Colombian Adults (Pneumo-CAP Colombia)
Who cites it
231 citing papers in PubMed, 18 syntheses or guidelines pooled it, 469 citations in OpenAlex.
- Prevalence and incidence of post-intensive care syndrome among intensive care unit survivors: a systematic review and meta-analysis.Annals of medicine · 2026Pooled it
- A core outcome measurement set for hyperemesis gravidarum research: a consensus study.BMC pregnancy and childbirth · 2026Pooled it
- The Effects of Inspiratory Muscle Training in Critically ill Adults: A Systematic Review and Meta-Analysis.Journal of intensive care medicine · 2026Pooled it
- A core outcome set for airway management research.Anaesthesia · 2026Pooled it
- Health-Related Quality of Life of Adult Sepsis Survivors Following Critical Illness: A Systematic Review.Critical care explorations · 2025Pooled it
- Reporting of nutritional screening, status, and intake in trials of nutritional and physical rehabilitation following critical illness: a systematic review.The American journal of clinical nutrition · 2025Pooled it
- Exploring the effectiveness of eHealth interventions in treating Post Intensive Care Syndrome (PICS) outcomes: a systematic review.Critical care (London, England) · 2024Pooled it
- An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2024Guideline
- Guideline on multimodal rehabilitation for patients with post-intensive care syndrome.Critical care (London, England) · 2023Guideline
- Pooled it
- Extracorporeal carbon dioxide removal in acute hypoxaemic respiratory failure: a systematic review, Bayesian meta-analysis and trial sequential analysis.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Core outcome measures for clinical effectiveness trials of nutritional and metabolic interventions in critical illness: an international modified Delphi consensus study evaluation (CONCISE).Critical care (London, England) · 2022Pooled it
- Patient-centred outcomes are under-reported in the critical care burns literature: a systematic review.Trials · 2022Pooled it
- Effectiveness and safety of inspiratory muscle training in patients with pulmonary hypertension: A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Between-trial heterogeneity in ARDS research.Intensive care medicine · 2021Pooled it
- Six-Minute Walk Distance After Critical Illness: A Systematic Review and Meta-Analysis.Journal of intensive care medicine · 2021Pooled it
- Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill people aged 65 and over: the 65 RCT.Health technology assessment (Winchester, England) · 2021Pooled it
- Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice.American journal of respiratory and critical care medicine · 2019Pooled it
- Effects of a brief primary care intervention for post-traumatic stress disorder symptoms after critical illness on health-related quality of life - A secondary analysis of the PICTURE randomised controlled trial.The European journal of general practice · 2026Trial
- Depressive symptoms are a key determinant of health-related quality of life in ICU survivors with psychological distress.Scientific reports · 2026Trial
171 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
rationaleResearch evaluating acute respiratory failure (ARF) survivors' outcomes after hospital discharge has substantial heterogeneity in terms of the measurement instruments used, creating barriers to synthesizing study data.
objectivesTo identify a minimum set of core outcome measures that are essential to include in all clinical research studies evaluating ARF survivors after discharge.
methodsWe conducted a three-round modified Delphi consensus process with 77 participants (47% female, 55% outside the United States), including clinical researchers from more than 16 countries across six continents, patients/caregivers, clinicians, and research funders. Participants reviewed standardized information on measure instruments for seven consensus-derived outcomes plus one recommended outcome. MEASUREMENTS AND MAIN
resultsResponse rates were 91 to 97% across the three rounds. Among 75 measurement instruments evaluated, the following met a priori consensus criteria: EQ-5D and 36-item Short Form Health Survey version 2 (optional) for the "satisfaction with life and personal enjoyment" and "pain" outcomes, and both the Hospital Anxiety and Depression Scale and the Impact of Events Scale-Revised for the "mental health" outcome. No measures reached consensus for the following outcomes: cognition, muscle and/or nerve function, physical function, and pulmonary function. All measures considered for pulmonary function met consensus criteria for exclusion. The following measures did not reach the threshold for consensus but achieved the highest scores for their respective outcomes: the Montreal Cognitive Assessment (cognition), manual muscle testing and handgrip dynamometry (muscle and/or nerve function), and 6-minute-walk test (physical function).
conclusionsThis Core Outcome Measurement Set is recommended for use in all clinical research evaluating ARF survivors after hospital discharge. In the future, researchers should evaluate measures for outcomes not reaching consensus.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.