Evidence map›Paper›PMID 28537249›Full record

ArticleMucosal immunology2018

Airway T cells protect against RSV infection in the absence of antibody.

E Kinnear, L Lambert, J U McDonald, H M Cheeseman, L J Caproni, J S Tregoning

Erratum issuedOpen access · bronzeAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 113 citations in OpenAlex.

  1. Trial
  2. Article
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  9. Lung-resident lymphocytes and their roles in respiratory infections and chronic respiratory diseases.Chinese medical journal pulmonary and critical care medicine · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Controlled Human Infection Challenge Studies with RSV.Current topics in microbiology and immunology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

E KinnearMucosal Infection and Immunity Group, Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, UK.
L LambertMucosal Infection and Immunity Group, Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, UK.
J U McDonaldMucosal Infection and Immunity Group, Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, UK.
H M CheesemanMucosal Infection and Immunity Group, Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, UK.
L J CaproniTouchlight Genetics, Morelands & Riverdale Buildings, Hampton, UK.
J S TregoningMucosal Infection and Immunity Group, Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, UK.
Imperial College London · GB

Funding

Medical Research Council MR/J006548/1
6 · The paper itself

Abstract

Tissue resident memory T (Trm) cells act as sentinels and early responders to infection. Respiratory syncytial virus (RSV)-specific Trm cells have been detected in the lungs after human RSV infection, but whether they have a protective role is unknown. To dissect the protective function of Trm cells, BALB/c mice were infected with RSV; infected mice developed antigen-specific CD8

Indexed as

Adoptive TransferAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCells, CulturedFemaleHumansImmunologic MemoryInterferon-gammaLungMiceMice, Inbred BALB CRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsRespiratory SystemTumor Necrosis Factor-alphaInterferon-gammaTumor Necrosis Factor-alphaVaccines, DNAViral Vaccines

Identifiers

PMID28537249
OpenAlexW2620154760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.