Evidence map›Paper›PMID 28536968›Full record

ArticleEJNMMI research2017

Clinical and imaging-based prognostic factors in radioembolisation of liver metastases from colorectal cancer: a retrospective exploratory analysis.

Kathy P Willowson, Aimee R Hayes, David L H Chan, Michael Tapner, Elizabeth J Bernard, Richard Maher, Nick Pavlakis, Stephen J Clarke, Dale L Bailey

Abstract read
In one paragraph

Article in EJNMMI research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Effects of dose heterogeneity on response and toxicity afterEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Quantitative evaluation ofMedical physics · 2024
    Article
  6. Article
  7. Article
  8. Trans-arterial Radioembolization Dosimetry in 2022.Cardiovascular and interventional radiology · 2022
    Review
  9. Article
  10. Radioembolization Dosimetry with Total-BodyJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  11. Article
  12. Article
  13. Comparison ofPhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2021
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Comparative dosimetry betweenEuropean journal of nuclear medicine and molecular imaging · 2020
    Article
  20. SimultaneousEJNMMI physics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kathy P WillowsonInstitute of Medical Physics, School of Physics, University of Sydney, Camperdown, NSW, Australia. kathy.willowson@sydney.edu.au.
Aimee R HayesDepartment of Nuclear Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia.
David L H ChanDepartment of Nuclear Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia.
Michael TapnerResearch and Development, Sirtex Medical Limited, North Sydney, Australia.
Elizabeth J BernardDepartment of Nuclear Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia.
Richard MaherDepartment of Radiology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Nick PavlakisDepartment of Medical Oncology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Stephen J ClarkeDepartment of Medical Oncology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Dale L BaileyDepartment of Nuclear Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate the relationship between absorbed dose and response of colorectal cancer liver metastases treated with [

methodsFDG PET/CT was used to measure response of individual lesions to a measured absorbed dose, derived from post-treatment

resultsSixty-three lesions were analysed from 22 patients. Poor agreement was seen between predicted and measured dose values. TLG was a superior measure of response, and all dose metrics were significant prognostic factors, with a D

conclusionsLesions receiving an average dose greater than 50 Gy are likely to have a significant response. For lesions receiving less than 50 Gy, dose heterogeneity is a significant prognostic factor. Lesions receiving an average dose less than 20 Gy are unlikely to respond. A reduction in TLG may be associated with improved overall survival.

Indexed as

90YDoseHeterogeneityRadioembolisationResponseSIRT

Identifiers

PMID28536968
PMCPMC5442040

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.