Observational studyClinical oral investigations2018
Oral health status in adult patients with newly diagnosed acute leukemia.
Observational study in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Periodontal Disease-Like Manifestations in Patients Having Acute Leukemia With Normal Complete Blood Counts.Case reports in dentistry · 2026Article
- Oral mucosal lesions in Polish patients with acute myeloid leukemia after allogeneic hematopoietic cell transplantation.Scientific reports · 2025Article
- Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study.PloS one · 2023Observational
- Assessment of oral health and care in head and neck oncology patients in King Faisal Specialist Hospital and Research Center-Jeddah.The Saudi dental journal · 2021Article
- Changes of Dentition State in Leukemic Patients during Chemotherapy.International journal of environmental research and public health · 2021Article
- Oral disorders in patients with newly diagnosed haematological diseases.Clinical oral investigations · 2020Article
- Oral Health-Related Quality of Life in Adult Patients with Newly Diagnosed Acute Leukaemia.Oral health & preventive dentistry · 2020Article
- Review
- Dental and Periodontal Treatment Need after Dental Clearance Is Not Associated with the Outcome of Induction Therapy in Patients with Acute Leukemia: Results of a Retrospective Pilot Study.Advances in hematology · 2020Article
- Gingival hyperplasia as an early manifestation of acute myeloid leukemia. A retrospective review.Journal of clinical and experimental dentistry · 2019Article
- Dissociations of oral foci of infections with infectious complications and survival after haematopoietic stem cell transplantation.PloS one · 2019Article
- Evaluation of oral manifestations and head and neck lymphadenopathy in newly diagnosed acute leukemia patients.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric DentistryArticle
- Oral manifestations of leukemia as part of early diagnosis.Hematology, transfusion and cell therapyReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this cross-sectional study was to evaluate the oral health of adult patients with newly diagnosed acute leukemia.
methodsPatients with initially diagnosed acute myeloid (AML) or lymphocytic (ALL) leukemia and a matched healthy control (HC) group were included. The oral investigation comprised inspection of the oral mucosa; the decayed (D), missing (M), and filled (F) teeth (DMF-T) index; and a detailed periodontal status. Subgingival biofilm samples were analyzed (polymerase chain reaction) for the presence of selected potentially periodontal pathogenic bacteria. Statistical analysis was performed using Fisher's exact test, chi-squared test, and Mann-Whitney U test (significance level α = 5%).
resultsThirty-nine patients with leukemia (AML 26, ALL 13) and 38 HCs were included. Oral mucosal findings were present in 62% of L compared to 0% of HC patients, whereby gingival hyperplasia was the most detected finding. Furthermore, a higher caries prevalence in leukemia patients was shown (D value 3.64 ± 3.98 vs. 0.72 ± 1.72, p < 0.01). The periodontal parameters were poorer in leukemia patients. No substantial differences in microbiological findings of selected bacteria were detected within L group and between L and HC patients.
conclusionThe high prevalence of oral diseases supports the demand of an early and consequent dental treatment of leukemia patients, especially considering subsequent therapy.
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